{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:28:47Z","timestamp":1777868927877,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,11,27]],"date-time":"2009-11-27T00:00:00Z","timestamp":1259280000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,11,27]],"date-time":"2009-11-27T00:00:00Z","timestamp":1259280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"abstract":"<jats:p>Creatine kinasebrain isoenzyme activity (CK-BB) was measured longitudinally in the serum of 31 pregnant women in the first stage of labor (early and advanced), at delivery, and 1, 6 and 24 h after delivery, in the umbilical cord and in the serum of their neonates on the first day of life. There was no increase in serum CK-BB values of mothers that delivered normally (n = 15) or had an elective cesarean section (n = 5). Pregnant women with signs of fetal distress had an increase in CK-BB levels in the first stage of labor (mean \u00b1 SD 4.5 \u00b1 4.9 U\/l, p &lt; 0.03) and 6 h after delivery (12 \u00b1 4 U\/l, p &lt; 0.0001). Neonates with intrauterine stress also had an increase in their CK-BB to 144 \u00b1 116 U\/l at 6 h of life, in comparison with babies born without signs of stress. It appears that CK-BB during labor and in the first hours of life may be indicative of intrauterine stress.<\/jats:p>","DOI":"10.1159\/000264182","type":"journal-article","created":{"date-parts":[[2009,11,30]],"date-time":"2009-11-30T03:50:28Z","timestamp":1259553028000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Significance of Creatine Kinase Isoenzymes for Fetal Asphyxia in Women at Labor"],"prefix":"10.1159","author":[{"given":"Styliani A.","family":"Andronikou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni B.","family":"Bairaktari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna-Despina","family":"Vasiliadou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Stefos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Lolis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Tsolas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.D.","family":"Lapatsanis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,11,27]]},"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000264182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:53:15Z","timestamp":1777553595000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000264182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000264182","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,27]]}}}