{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:02:58Z","timestamp":1777888978975,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,12,16]],"date-time":"2009-12-16T00:00:00Z","timestamp":1260921600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,12,16]],"date-time":"2009-12-16T00:00:00Z","timestamp":1260921600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynakol Rundsch"],"abstract":"<jats:p>20 women, age 23\u201349, with culture-confirmed vaginal trichomoniasis were treated on 3 consecutive nights with 5 g of 2% tioconazole vaginal cream, a new imidazole antifungal agent. 4 days following the last administration, 14 patients (70%) had a negative culture for Trichomonas vaginalis. 1 month after entering the study, no relapses were observed and 16 (80%) had negative cultures; only one relapse was noted on long-term (60-day) follow-up. Typical signs and symptoms were severe or moderately severe at baseline in nearly all patients. At 30-day and 60-day follow-up, they were either absent or mild in the patients reporting any symptoms. A burning sensation in 2 patients was the only reported side effect. In separate global evaluations by the physician and the patients, the overall clinical effect was considered satisfactory in all but 1 patient. These results indicate that tioconazole is safe and effective in a short-course treatment of vaginal infection caused by T. vaginalis.<\/jats:p>","DOI":"10.1159\/000269569","type":"journal-article","created":{"date-parts":[[2009,12,17]],"date-time":"2009-12-17T05:06:32Z","timestamp":1261026392000},"page":"37-41","source":"Crossref","is-referenced-by-count":0,"title":["Short-Term Treatment of Trichomonas vaginalis with Tioconazole Cream, a New Antifungal Agent"],"prefix":"10.1159","author":[{"given":"C.A.","family":"Yoffe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.A.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,12,16]]},"container-title":["Gyn\u00e4kologische Rundschau"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000269569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:04:14Z","timestamp":1777611854000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000269569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12,16]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000269569","archive":["Portico"],"relation":{},"ISSN":["0017-6001","2571-6484"],"issn-type":[{"value":"0017-6001","type":"print"},{"value":"2571-6484","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12,16]]}}}