{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:24:39Z","timestamp":1777890279143,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T00:00:00Z","timestamp":1261526400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T00:00:00Z","timestamp":1261526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gyn\u00e4kol Geburtshilfliche Rundsch"],"abstract":"<jats:p>Fragestellung: Innerhalb einer Studie zur Ovulationsinduktion mittels Opiatrezeptorblockade untersuchten wir Aktivit\u00e4t und Reaktivit\u00e4t der hypothalamisch-hypophys\u00e4radrenalen Achse bei Frauen mit hypothalamischer Amenorrh\u00f6. Methoden: Die Blockade der Opiatrezeptoren erfolgte durch die t\u00e4gliche Gabe von 4 mg Naloxon. Ergebnisse: Die Kortisolantwort im Naloxontest brachte sehr unterschiedliche Reaktionsmuster, unabh\u00e4ngig vom hypo-thalamischen Opiodtonus. Ein Hyperkortisolismus fand sich nicht. Die basalen Kortisol- und DHEAS-Spiegel zeigten unspezif\u00edsche Ver\u00e4nderungen. Schlussfolgerungen: Nach unseren Ergebnissen k\u00f6nnen keine eindeutigen Beziehungen zwischen Opiodtonus und adrenaler Funktionslage abgeleitet werden.<\/jats:p>","DOI":"10.1159\/000272521","type":"journal-article","created":{"date-parts":[[2009,12,24]],"date-time":"2009-12-24T03:16:40Z","timestamp":1261624600000},"page":"194-198","source":"Crossref","is-referenced-by-count":0,"title":["Der Einfluss endogener Opioide auf die Nebennierenrindenaktivit\u00e4t bei Frauen mit hypothalamischer Amenorrh\u00f6"],"prefix":"10.1159","author":[{"given":"Barnd Th","family":"Krause","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylke","family":"M\u00f6ller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,12,23]]},"container-title":["Gyn\u00e4kologisch-geburtshilfliche Rundschau"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000272521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:33:52Z","timestamp":1777613632000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000272521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000272521","archive":["Portico"],"relation":{},"ISSN":["1018-8843","1423-0011"],"issn-type":[{"value":"1018-8843","type":"print"},{"value":"1423-0011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12,23]]}}}