{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:34:19Z","timestamp":1777944859623,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,1,8]],"date-time":"2010-01-08T00:00:00Z","timestamp":1262908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,1,8]],"date-time":"2010-01-08T00:00:00Z","timestamp":1262908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"abstract":"<jats:p>In this random study, 60 patients were given either cefotaxime, or ceftriaxone as a prophylactic measure in cervicofacial surgery. Each antibiotic was administered during a 48-hour period starting 1 h before the operation. Twenty-three patients underwent major cervicofacial surgery including opening of the pharynx or the buccal cavity by the cervical route. Only a single postoperative infection was observed as a result of a salivary fistula on the 2nd postoperative day. The two antibiotics have turned out to be very efficient as short-term prophylactic treatment in cervicofacial surgery. In other respects, the much longer half-life of ceftriaxone means that a single daily dose can be given. Finally, the cost of the prophylactic treatment is smaller using ceftriaxone than cefotaxime.<\/jats:p>","DOI":"10.1159\/000275928","type":"journal-article","created":{"date-parts":[[2010,1,11]],"date-time":"2010-01-11T03:13:29Z","timestamp":1263179609000},"page":"152-156","source":"Crossref","is-referenced-by-count":6,"title":["Antimicrobial Prophylaxis in Head and Neck Surgery"],"prefix":"10.1159","author":[{"given":"E.","family":"Panosetti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Lehmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.C.","family":"Smolik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,1,8]]},"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000275928","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:20:02Z","timestamp":1777710002000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000275928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000275928","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,8]]}}}