{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:33:29Z","timestamp":1777944809911,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,1,8]],"date-time":"2010-01-08T00:00:00Z","timestamp":1262908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,1,8]],"date-time":"2010-01-08T00:00:00Z","timestamp":1262908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"abstract":"<jats:p>The characteristics of Reissner\u2019s membrane from 47 human cochleae with mild endolymphatic hydrops, profound sensorineural deafness and normal ears were studied by light microscopy. The highest cell densities were observed in the zones adjacent to the limbus spiralis and the stria vascularis. The cell density of Reissner\u2019s in normal ears decreased with age concomitant with an increased formation of epithelial cell clusters. In hydrops, the density increased with the exception of the apical turn. However, sporadic loss of the cells in isolated areas of the membrane was observed. The ears with profound deafness showed no significant changes compared with age-related controls. No definite relationship between Reissner\u2019s cell density and hair cell loss or strial atrophy was observed.<\/jats:p>","DOI":"10.1159\/000276150","type":"journal-article","created":{"date-parts":[[2010,1,11]],"date-time":"2010-01-11T03:13:29Z","timestamp":1263179609000},"page":"273-280","source":"Crossref","is-referenced-by-count":5,"title":["Reissner\u2019s Membrane in Aging, Meni\u00e8re\u2019s Disease, and Profound Sensorineural Deafness"],"prefix":"10.1159","author":[{"given":"Mario L.","family":"Quijano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen B.","family":"Fowler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,1,8]]},"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000276150","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:23:22Z","timestamp":1777710202000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000276150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000276150","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,8]]}}}