{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:33:59Z","timestamp":1777944839188,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,1,13]],"date-time":"2010-01-13T00:00:00Z","timestamp":1263340800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,1,13]],"date-time":"2010-01-13T00:00:00Z","timestamp":1263340800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"abstract":"<jats:p>Using 110 male albino guinea pigs, and applying electrophysiological methods, we investigated the effects of 4 kHz tone at moderate sound pressure level on the inner ear at different exposure times (6, 12, 24 and 48 h). Longer than 12 h exposure to 4 kHz tone had a considerable effect on the hearing, inducing a decrease in the maximum output voltage of cochlear microphonics and an increase in the K+ concentration in the endolymph.<\/jats:p>","DOI":"10.1159\/000276670","type":"journal-article","created":{"date-parts":[[2010,1,15]],"date-time":"2010-01-15T03:25:48Z","timestamp":1263525948000},"page":"263-268","source":"Crossref","is-referenced-by-count":6,"title":["Effect of 4 kHz Tone Exposure on the Guinea Pig Inner Ear: Relation in the Change of Cochlear Microphonics, Action Potential, Electrochemical Potential and K\n                    <sup>+<\/sup>\n                    Ion Concentration Induced by Noise Exposure"],"prefix":"10.1159","author":[{"given":"T.","family":"Sugisawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Nemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Inada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yamamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,1,13]]},"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000276670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:28:31Z","timestamp":1777710511000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000276670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,13]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000276670","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,13]]}}}