{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:03:44Z","timestamp":1777871024756,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,2,2]],"date-time":"2010-02-02T00:00:00Z","timestamp":1265068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,2,2]],"date-time":"2010-02-02T00:00:00Z","timestamp":1265068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"abstract":"<jats:p>We injected 20 \u00b5g of prostaglandin E&lt;sub&gt;1&lt;\/sub&gt; (PGE&lt;sub&gt;1&lt;\/sub&gt;) intracavernously in 32 patients with impotence, we then examined penile blood flow using a Xe-133 washout technique. In addition, we also performed a cavernosography. After PGE&lt;sub&gt;1&lt;\/sub&gt; injection, 18 patients (56%) showed complete erection, 10 (31 %) tumescence, and 4 (13%) no response. Fourteen patients who presented either an inadequate or no response to PGE&lt;sub&gt;1&lt;\/sub&gt; injection were suspected to have vasculogenic impotence. Cavernosography of patients who showed good response after PGE&lt;sub&gt;1&lt;\/sub&gt; injection demonstrated no obvious venous leakage. In this group penile blood flow decreased after full erection. However, 7 patients (50%) suspected to have vascular problems showed venous leakage. Subsequently, these 7 patients appeared to be cases of venous incompetence. The penile blood flow of these 7 patients before or after PGE&lt;sub&gt;1&lt;\/sub&gt; injection was not statistically different from that of other groups. Based on these findings, cavernosography after PGE&lt;sub&gt;1&lt;\/sub&gt; injection appears to be useful for differentiating the venous factor of impotence.<\/jats:p>","DOI":"10.1159\/000282131","type":"journal-article","created":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T05:55:56Z","timestamp":1265176556000},"page":"193-196","source":"Crossref","is-referenced-by-count":3,"title":["Intracavernous Injection of Prostaglandin E\n                    <sub>1<\/sub>\n                    The Application to Cavernosography and Penile Blood Flow Measurement for the Diagnosis of Venogenic Impotence"],"prefix":"10.1159","author":[{"given":"Manabu","family":"Ishigooka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Irisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhisa","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruhiro","family":"Nakada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,2,2]]},"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000282131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T16:57:37Z","timestamp":1777568257000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000282131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,2]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000282131","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,2]]}}}