{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:03:48Z","timestamp":1777871028843,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T00:00:00Z","timestamp":1265155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T00:00:00Z","timestamp":1265155200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"abstract":"<jats:p>We have studied peripheral blood samples for chromosomal anomalies in 110 consecutive patients who had cryptorchidism and\/or hypospadias. Of the patients 7 (6.4%) were found to have chromosomal anomalies. The incidence of chromosomal anomalies in patients with cryptorchidism only was 4\/83 (4.8%), in patients with hypospadias only the incidence was 1\/18 (5.6%) and in concomitant cases the incidence was 2\/9 (22.2%). Of 69 patients with cryptorchidism and\/or hypospadias who did not have any other congential abnormalities, 3 patients (4.3%) were found to have sex chromosomal anomalies. However, of 41 patients associated with generalized congenital abnormalities including mental and growth retardation, we found 4 patients (9.8%) with autosomal anomalies. We conclude that most children with multiple associated abnormalities other than cryptorchidism and\/or hypospadias should have chromosome analysis. Moreover, attention should be paid to sex chromosomal anomalies, even when patients with cryptorchidism and\/or hypospadias do not have any associated generalized physical anormalities.<\/jats:p>","DOI":"10.1159\/000282187","type":"journal-article","created":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T05:55:56Z","timestamp":1265176556000},"page":"60-63","source":"Crossref","is-referenced-by-count":38,"title":["Chromosomal Anomalies in Cryptorchidism and Hypospadias"],"prefix":"10.1159","author":[{"given":"Takanori","family":"Yamaguchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichiro","family":"Kitada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Osada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,2,3]]},"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000282187","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T16:58:00Z","timestamp":1777568280000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000282187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,3]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000282187","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,3]]}}}