{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:45:37Z","timestamp":1777891537515,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,2,26]],"date-time":"2010-02-26T00:00:00Z","timestamp":1267142400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,2,26]],"date-time":"2010-02-26T00:00:00Z","timestamp":1267142400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"abstract":"<jats:p>The feasibility of ultrasound-guided transvaginal interstitial laser treatment of the ovary (TILT) and its efficacy for ovulation induction was investigated in 3 hormone-therapy-resistant patients with chronic hyperandrogenic anovulation. TILT was performed at powers of 1\u20132 W and exposures of 75-600 s. Clear-cut hyperechogenic zones developed during laser irradiation with diameters of up to 13.7 mm. Spontaneous ovulation and\/or hormonal changes after TILT did not occur. No adhesion formation was seen during a laparoscopy or laparotomy in 2 patients 6 months after TILT. In conclusion, TILT of the ovaries was simple to perform but so far the clinical results are disappointing. Further studies with a modified technique are necessary to further investigate the efficacy of TILT.<\/jats:p>","DOI":"10.1159\/000291500","type":"journal-article","created":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T04:20:23Z","timestamp":1267417223000},"page":"115-119","source":"Crossref","is-referenced-by-count":4,"title":["Transvaginal Interstitial Laser Treatment of the Ovary for the Management of Chronic Hyperandrogenic Anovulation: First Clinical Experience"],"prefix":"10.1159","author":[{"given":"Eugenie","family":"Kaaijk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fulco","family":"van der Veen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan F.","family":"Beek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J.C.","family":"van Gemert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frits B.","family":"Lammes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,2,26]]},"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000291500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:05:55Z","timestamp":1777615555000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000291500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,26]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000291500","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,26]]}}}