{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T23:02:06Z","timestamp":1769554926351,"version":"3.49.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Little is known about proper interval periods between the flushings of totally implantable access ports after completion of chemotherapy. Manufacturer guidelines recommend flushing catheters every 4 weeks. &lt;i&gt;Methods:&lt;\/i&gt; This retrospective study examined whether flushing less than every 4 weeks conferred any benefit. &lt;i&gt;Results:&lt;\/i&gt; 349 totally implanted access ports were divided into four groups based on the different durations of the intervals between flushings. Sixteen (4.6%) complications were observed in the study population. &lt;i&gt;Conclusion:&lt;\/i&gt; Our results demonstrate that extending the flushing interval to up to 4 months remains medically safe and drastically reduces the costs.<\/jats:p>","DOI":"10.1159\/000294919","type":"journal-article","created":{"date-parts":[[2010,3,11]],"date-time":"2010-03-11T09:26:54Z","timestamp":1268299614000},"page":"91-94","source":"Crossref","is-referenced-by-count":39,"title":["Interval between Port Catheter Flushing Can Be Extended to Four Months"],"prefix":"10.1159","volume":"70","author":[{"given":"Atanas","family":"Ignatov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Ignatov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Taran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobbie","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serban-Dan","family":"Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Bischoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,3,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS1072-7515%2800%2900690-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.113.1.165"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1634%2Ftheoncologist.9-2-207"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.163.16.1913"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0720-048X%2895%2900633-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.271.13.1014"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.146.10.1949"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007%2Fs005200050303"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1080%2F07357900500276923"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2354.2008.00973.x"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/294919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/294919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T20:07:07Z","timestamp":1745438827000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000294919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2010,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000294919","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}