{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:09:24Z","timestamp":1777892964626,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,3,16]],"date-time":"2010-03-16T00:00:00Z","timestamp":1268697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,3,16]],"date-time":"2010-03-16T00:00:00Z","timestamp":1268697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"abstract":"<jats:p>Plasma cAMP was determined using the method of Toveyetal. in normal pregnant women with a mean concentration of 18.9 \u00b1 0.8 pmol\/ml (x \u00b1 SEM). Between weeks 9\u201312 and 33\u201336 of gestation, there were two peaks, with a mean cAMP of 22.5 \u00b1 2.4, which were significantly increased in comparison to the other weeks of pregnancy. Significantly decreased values were found in patients with threatened abortion (weeks 12\u201328) which terminated in abortion (11.6 \u00b1 2.4; p &lt; 0.01). In premature labor no differences were found. During therapy with fenoterol there were highly significantly increased plasma cAMP levels (48.2 \u00b1 2.8; p &lt; 0.0005). During thyroid hormone therapy in euthyroid goiter, cAMP was significantly decreased (14.0 \u00b1 1.4; p &lt; 0.05). 1 week after cessation of therapy a highly significant increase of cAMP was observed (38.2 \u00b1 6.9; p &lt; 0.0005). There was a negative linear regression between T&lt;sub&gt;3&lt;\/sub&gt; and cAMP ( 2p &lt; 0.01). In pregnancy with hypertension cAMP was significantly elevated (30.5 \u00b1 3.8; p &lt; 0.0005), but nearly normal under antihypertensive therapy. In pregnancy with edema only, no difference was found. Induction of labor with PGE&lt;sub&gt;2&lt;\/sub&gt;&lt;sub&gt;\u0391&lt;\/sub&gt; was followed by a decrease of plasma cAMP.<\/jats:p>","DOI":"10.1159\/000299847","type":"journal-article","created":{"date-parts":[[2010,3,17]],"date-time":"2010-03-17T05:58:36Z","timestamp":1268805516000},"page":"274-285","source":"Crossref","is-referenced-by-count":3,"title":["Plasma cAMP in Normal and Abnormal Human Pregnancy"],"prefix":"10.1159","author":[{"given":"R.","family":"G\u00f6ser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Jaschonek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Kindler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Keller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.E.","family":"Schindler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,3,16]]},"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000299847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:41:59Z","timestamp":1777617719000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000299847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,16]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000299847","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,16]]}}}