{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:17:38Z","timestamp":1783639058264,"version":"3.55.0"},"reference-count":14,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; The incidence of skin cancer and especially basal cell carcinoma (BCC) has increased in the last few decades. The gold standard of care is usually a surgical excision, but it also has the risk of local recurrence depending on tumor characteristics. &lt;i&gt;Objectives:&lt;\/i&gt; We analyzed the 5-year cure rates after surgical excision of BCC with complete margin control using paraffin-embedded sections. &lt;i&gt;Methods:&lt;\/i&gt; A retrospective analysis of 671 patients (45.3% male, 54.7% female) with 777 primary and 85 with recurrent BCC were collected during 2001\u20132003. All patients underwent surgery with complete margin control using paraffin-embedded sections. When the histological examination revealed a positive margin, another surgical step was performed in the area of residual tumor. &lt;i&gt;Results:&lt;\/i&gt; Five-year follow-up examinations were possible in 630\/862 (73.1%) of patients with BCC. In the group with primary BCC (n = 562), 3 tumor recurrences (0.5%) were identified; in the group with recurrent BCC (n = 68), 2 tumor recurrences (2.9%) were seen, resulting in an overall 5-year recurrence rate of 0.8% for all patients with BCC. The mean tumor recurrence time after surgery was 36.6 months. &lt;i&gt;Conclusion:&lt;\/i&gt; Local complete tumor resection confirmed by complete margin control using paraffin-embedded sections can achieve excellent cure rates for both primary and recurrent BCC.<\/jats:p>","DOI":"10.1159\/000300116","type":"journal-article","created":{"date-parts":[[2010,5,17]],"date-time":"2010-05-17T08:17:14Z","timestamp":1274084234000},"page":"363-369","source":"Crossref","is-referenced-by-count":29,"title":["Surgical Excision of Basal Cell Carcinoma with Complete Margin Control: Outcome at 5-Year Follow-Up"],"prefix":"10.1159","volume":"220","author":[{"given":"T.","family":"Wetzig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Woitek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Eichhorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Paasch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,5,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2006.07234.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2007.04.034"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.119.9.761"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2005.04.087"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2005.04.083"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00101-007-1169-x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2006.07.007"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.138.8.1043"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2165%2F00128071-200203040-00003"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2004.06047.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2008.09021.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS1470-2045%2808%2970260-2"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS1470-2045%2808%2970292-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2804%2917399-6"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/300116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/300116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T20:01:04Z","timestamp":1745438464000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000300116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2010,6,1]]},"published-print":{"date-parts":[[2010,6,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000300116","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}