{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:15:56Z","timestamp":1784265356092,"version":"3.55.0"},"reference-count":3,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gyn\u00e4kol Geburtshilfliche Rundsch"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Die HAPO-Studie (Hyperglycemia and Adverse Pregnancy Outcome Study) ist eine weltweite Studie, in die 25 000 Schwangere aufgenommen wurden und die im Juni 2008 ver\u00f6ffentlicht wurde [NEJM 2008;358:2061\u20132063]. Die Ergebnisse wurden von der Fachwelt heiss ersehnt, da man sich entscheidende Erkenntnisse \u00fcber die Auswirkungen von erh\u00f6hten Blutzuckerwerten bei der Mutter auf das ungeborene Kind erhofft. Es ist zudem zu erwarten, dass auf der Basis dieser Studie die diagnostischen Kriterien f\u00fcr Schwangerschaftsdiabetes modifiziert werden. Die HAPO-Studie wird die an den massgeblichen intrauterinen kindlichen Komplikationen orientierten Grenzwerte f\u00fcr den oralen Glukosetoleranztest in der Schwangerschaft liefern, die auf einem sehr hohen Evidenzniveau erhoben wurden. Das wird die Diagnostik des Gestationsdiabetes vereinheitlichen und dem betreuenden Arzt mehr fachliche und rechtliche Sicherheit bieten.<\/jats:p>","DOI":"10.1159\/000301083","type":"journal-article","created":{"date-parts":[[2010,5,20]],"date-time":"2010-05-20T07:28:17Z","timestamp":1274340497000},"page":"254-258","source":"Crossref","is-referenced-by-count":2,"title":["Bedeutung der HAPO-Ergebnisse f\u00fcr die zuk\u00fcnftige Diagnostik und Therapie des Gestationsdiabetes"],"prefix":"10.1159","volume":"49","author":[{"given":"Ute","family":"Sch\u00e4fer-Graf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,5,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMe0802623"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa0902430"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2337%2Fdc09-1848"}],"container-title":["Gyn\u00e4kologisch-geburtshilfliche Rundschau"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/301083","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/301083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T20:11:49Z","timestamp":1745439109000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000301083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":3,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2010,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000301083","archive":["Portico"],"relation":{},"ISSN":["1018-8843","1423-0011"],"issn-type":[{"value":"1018-8843","type":"print"},{"value":"1423-0011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}