{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:26:05Z","timestamp":1761960365734,"version":"build-2065373602"},"reference-count":19,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res Paediatr"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Aims:&lt;\/i&gt; To determine if primary hyperparathyroidism (pHPT) per se may be responsible of hypercalcitoninemia. pHPT induces chronic hypercalcemia that should be expected to be a potential stimulatory pathway of calcitonin (CT) secretion and to cause hypercalcitoninemia. &lt;i&gt;Method:&lt;\/i&gt; We studied relationships between CT and pHPT-related chronic hypercalcemia in 122 patients aged 25\u201383 years who underwent parathyroid surgery. CT, calcium and PTH plasma levels were measured in all patients preoperatively. CT was measured by a current immunometric assay specific of mature CT monomer. &lt;i&gt;Results:&lt;\/i&gt; Of our 122 patients with pHPT-related hypercalcemia, 120 (98.4%) had normal CT values of less than 10 pg\/ml and two (1.6%) exhibited a mildly increased CT above 10 pg\/ml (11 and 12 pg\/ml, respectively). We evidenced no relationship between CT and calcium level or PTH level. &lt;i&gt;Conclusions:&lt;\/i&gt; Chronic pHPT-related hypercalcemia per se does not cause hypercalcitoninemia. The finding of pHPT concomitant with high CT levels should raise suspicion of multiple endocrine neoplasia type 2A.<\/jats:p>","DOI":"10.1159\/000308170","type":"journal-article","created":{"date-parts":[[2010,4,14]],"date-time":"2010-04-14T06:58:14Z","timestamp":1271228294000},"page":"372-375","source":"Crossref","is-referenced-by-count":7,"title":["Could Primary Hyperparathyroidism-Related Hypercalcemia Induce Hypercalcitoninemia?"],"prefix":"10.1159","volume":"73","author":[{"given":"B.","family":"Conte-Devolx","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Morlet-Barla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Roux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Sebag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.F.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Niccoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,4,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1385%2FENDO%3A21%3A3%3A201"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1432-1033.1984.tb07996.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2362.2002.01052.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1359%2FJBMR.051210"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.76.6.1489"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1210%2Fjcem-63-3-785"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-0029-1210708"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1210%2Fjcem-49-2-223"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2265.1981.tb02751.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000180309"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.86.12.5658"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.78.1.114"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2003-030709"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fjbmr.5650010407"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1530%2FEJE-07-0566"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.86.7.3091"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM198708273170904"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1677%2Fjoe.0.1340141"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1089%2F105072503321086962"}],"container-title":["Hormone Research in Paediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/308170","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/308170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T20:03:05Z","timestamp":1745438585000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000308170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2010,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000308170","archive":["Portico"],"relation":{},"ISSN":["1663-2818","1663-2826"],"issn-type":[{"type":"print","value":"1663-2818"},{"type":"electronic","value":"1663-2826"}],"subject":[],"published":{"date-parts":[[2010]]}}}