{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T18:36:43Z","timestamp":1784313403969,"version":"3.55.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"abstract":"<jats:p>The authors report the results of an experimental study of a series of 16 rabbit eyes that underwent prolonged tamponade by a liquid perfluorocarbon (LPFC). After vitreous compression by C&lt;sub&gt;3&lt;\/sub&gt;F&lt;sub&gt;8&lt;\/sub&gt;, a complete gas\/LPFC exchange is performed and left in place for 48 h, 12 days and 21 days. Study of the retina by light and electron microscopy showed numerous lesions: vacuolization in the nerve fiber layer, progressive defects of the outer photoreceptor segments and presence of pseudomyelinic bodies in the inner plexiform layer. The axonal fiber loss is shown by a specific marker. The analysis of the results underlines the mechanical toxicity of LPFCs used in prolonged tamponade, which are too heavy for the neurosensory retina.<\/jats:p>","DOI":"10.1159\/000310648","type":"journal-article","created":{"date-parts":[[2010,4,6]],"date-time":"2010-04-06T22:56:00Z","timestamp":1270594560000},"page":"306-314","source":"Crossref","is-referenced-by-count":21,"title":["Experimental Tolerance to Perfluorodecalin Used in Prolonged Intraocular Tamponade"],"prefix":"10.1159","author":[{"given":"F.","family":"Devin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Jourdan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.B.","family":"Saracco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Lucciani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,4,1]]},"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000310648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:12:37Z","timestamp":1777705957000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000310648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,1]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000310648","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,1]]}}}