{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:19:04Z","timestamp":1792523944404,"version":"4.5.0"},"reference-count":49,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; A considerable number of pollen-allergic patients develops allergy to plant foods, which has been attributed to cross-reactivity between food and pollen allergens. The aim of this study was to analyze the differences among pollen-allergic patients with and without plant food allergy. &lt;i&gt;Methods:&lt;\/i&gt; Eight hundred and six patients were recruited from 8 different hospitals. Each clinical research group included 100 patients (50 plant food-allergic patients and 50 pollen-allergic patients). Diagnosis of pollen allergy was based on typical case history of pollen allergy and positive skin prick tests. Diagnosis of plant-food allergy was based on clear history of plant-food allergy, skin prick tests and\/or plant-food challenge tests. A panel of 28 purified allergens from pollens and\/or plant foods was used to quantify specific IgE (ADVIA-Centaur\u00ae platform). &lt;i&gt;Results:&lt;\/i&gt; Six hundred and sixty eight patients (83%) of the 806 evaluated had pollen allergy: 396 patients with pollen allergy alone and 272 patients with associated food and pollen allergies. A comparison of both groups showed a statistically significant increase in the food and pollen allergy subgroup in frequency of: (1) asthma (47 vs. 59%; p &lt; 0.001); (2) positive skin test results to several pollens: &lt;i&gt;Plantago,&lt;\/i&gt;&lt;i&gt;Platanus,&lt;\/i&gt;&lt;i&gt;Artemisia,&lt;\/i&gt;&lt;i&gt;Betula,&lt;\/i&gt;&lt;i&gt;Parietaria &lt;\/i&gt;and&lt;i&gt; Salsola &lt;\/i&gt;(p &lt; 0.001); (3) sensitization to purified allergens: Pru p 3, profilin, Pla a 1 \u2013 Pla a 2, Sal k 1, PR-10 proteins and Len c 1. &lt;i&gt;Conclusion:&lt;\/i&gt; Results showed relevant and significant differences between both groups of pollen-allergic patients depending on whether or not they suffered from plant-derived food allergy.<\/jats:p>","DOI":"10.1159\/000312636","type":"journal-article","created":{"date-parts":[[2010,4,26]],"date-time":"2010-04-26T06:56:19Z","timestamp":1272264979000},"page":"182-192","source":"Crossref","is-referenced-by-count":56,"title":["Differences among Pollen-Allergic Patients with and without Plant Food Allergy"],"prefix":"10.1159","volume":"153","author":[{"given":"Javier","family":"Cuesta-Herranz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domingo","family":"Barber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Cistero-Bah\u00edma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas F.","family":"Crespo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Fern\u00e1ndez-Rivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Fern\u00e1ndez-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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