{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T16:17:29Z","timestamp":1776701849377,"version":"3.51.2"},"reference-count":22,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Surg"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Background\/Aims:&lt;\/i&gt; Vacuum-assisted closure (VAC) leads to a high fascial closure rate in open abdomen within the first week of treatment. However, little data exist on the role of long-term VAC treatment in patients with peritonitis, where fascial closure cannot be accomplished within the first days. &lt;i&gt;Methods:&lt;\/i&gt; We reviewed the medical records of 49 patients with open abdomen for more than 7 days due to secondary peritonitis, who underwent a VAC-treatment. Nonparametric analysis was performed using \u03c7&lt;sup&gt;2&lt;\/sup&gt; test or Fisher\u2019s exact test. &lt;i&gt;Results:&lt;\/i&gt; Fascial closure could be accomplished in only 11 patients (22%), whereas complications occurred in 43 patients (88%). Re-explorations after starting VAC were associated with the occurrence of enterocutaneous fistula (p &lt; 0.001) and were also of prognostic value regarding the rate of fascial closure (p = 0.033). &lt;i&gt;Conclusions:&lt;\/i&gt; If fascial closure cannot be accomplished within the first days, patients show a dramatically lower fascial closure and an increased complication rate with VAC. Further studies are needed to evaluate whether this subgroup really benefits from VAC.<\/jats:p>","DOI":"10.1159\/000314609","type":"journal-article","created":{"date-parts":[[2010,7,22]],"date-time":"2010-07-22T07:08:09Z","timestamp":1279782489000},"page":"272-278","source":"Crossref","is-referenced-by-count":35,"title":["Long-Term Vacuum-Assisted Closure in Open Abdomen due to Secondary Peritonitis: A Retrospective Evaluation of a Selected Group of Patients"],"prefix":"10.1159","volume":"27","author":[{"given":"Moritz","family":"Schmelzle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Alldinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanno","family":"Matthaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feride","family":"Aydin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Wallert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus F.","family":"Eisenberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Schulte am Esch, II","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levent","family":"Dizdar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan A.","family":"Topp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram T.","family":"Knoefel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,7,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00268-008-9805-4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jamcollsurg.2007.05.015"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000102411.69521.80"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00104-006-1206-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jamcollsurg.2006.12.039"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F01.sla.0000124291.09032.bf"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00104-008-1485-y"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000115065.39699.6A"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjsurg.2006.04.010"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjsurg.2005.11.013"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000149248.02598.9E"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjsurg.2006.04.010"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjsurg.2005.09.003"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000149248.02598.9E"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2F01.ta.0000196004.49422.af"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2006-921490"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-200002000-00001"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000100218.03754.6A"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-200002000-00001"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000102411.69521.80"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097%2F01.sap.0000237643.45125.8b"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00268-008-9796-1"}],"container-title":["Digestive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/314609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/314609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:22:24Z","timestamp":1745436144000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000314609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2010,8,1]]},"published-print":{"date-parts":[[2010,8,30]]}},"URL":"https:\/\/doi.org\/10.1159\/000314609","archive":["Portico"],"relation":{},"ISSN":["0253-4886","1421-9883"],"issn-type":[{"value":"0253-4886","type":"print"},{"value":"1421-9883","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}