{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:56:40Z","timestamp":1777521400638,"version":"3.51.4"},"reference-count":20,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2010,8,7]],"date-time":"2010-08-07T00:00:00Z","timestamp":1281139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,8,7]],"date-time":"2010-08-07T00:00:00Z","timestamp":1281139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Our purpose was to report the results of 1-year follow-up examinations after intravitreal bevacizumab injection for the treatment of chronic central serous chorioretinopathy (CSC). &lt;i&gt;Methods:&lt;\/i&gt; Five eyes in 5 patients with chronic CSC were intravitreally injected with 1.25 mg\/0.05 ml of bevacizumab. The need for retreatment was evaluated if spectral-domain optical coherence tomography showed the presence of subretinal fluid at the time of a 1-month follow-up examination. Best-corrected visual acuity and central foveal thickness were compared between baseline and 1 year after the first injection. &lt;i&gt;Results:&lt;\/i&gt; The mean logarithm of the minimum angle of resolution (logMAR) best-corrected visual acuity improved from 0.23 \u00b1 0.46 to 0.17 \u00b1 0.47 and the mean central foveal thickness significantly decreased from 323 \u00b1 98 \u00b5m to 171 \u00b1 63 \u00b5m (p &lt; 0.05). &lt;i&gt;Conclusion:&lt;\/i&gt; The intravitreal injection of bevacizumab is well tolerated in maintaining vision and reducing serous retinal detachment in patients with chronic CSC, as evaluated at a 1-year follow-up examination.<\/jats:p>","DOI":"10.1159\/000314709","type":"journal-article","created":{"date-parts":[[2010,8,9]],"date-time":"2010-08-09T06:56:32Z","timestamp":1281336992000},"page":"37-40","source":"Crossref","is-referenced-by-count":42,"title":["Results of One-Year Follow-Up Examinations after Intravitreal Bevacizumab Administration for Chronic Central Serous Chorioretinopathy"],"prefix":"10.1159","volume":"225","author":[{"given":"Maiko","family":"Inoue","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuaki","family":"Kadonosono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichiro","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Yamane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Arakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,8,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-200202000-00004"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9394%2802%2901438-1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-199616030-00004"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajo.2009.01.024"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00417-008-0856-x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038%2Feye.2008.55"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e3181bcf0b4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1089%2Fjop.2006.22.145"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e318050ca69"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0161-6420%2802%2901157-0"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00417-005-0175-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3341%2Fkjo.2006.20.2.131"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-200304000-00016"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-200312000-00002"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-200602000-00027"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.87.12.1453"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10384-008-0613-z"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2FIAE.0b013e3181be0a83"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1210%2Fer.2003-0027"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ophtha.2008.04.023"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/314709","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/314709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:23:08Z","timestamp":1745436188000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000314709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,7]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,12,1]]},"published-print":{"date-parts":[[2010,12,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000314709","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,7]]}}}