{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:55:47Z","timestamp":1791122147207,"version":"4.1.0"},"reference-count":34,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; CLOX, a clock drawing test protocol uniquely sensitive to impairment of executive functions, has been proposed as a screening tool for mild cognitive impairment (MCI), but data about its diagnostic efficiency are lacking. &lt;i&gt;Methods:&lt;\/i&gt; There are data for 196 subjects, age \u226760 years, referred to a memory clinic for cognitive complaints. After extensive neuropsychological testing, 64 were diagnosed as cognitively normal and 132 with MCI. &lt;i&gt;Results:&lt;\/i&gt; At standard cutoffs, both CLOX subtests had a fair specificity (CLOX1 72%, CLOX2 92%) but unacceptably low values of sensitivity (CLOX1 54%, CLOX2 28%) and likelihood ratio (CLOX1 1.91, CLOX2 3.59) for MCI. The use of different cutoffs or the combination of CLOX with the Mini-Mental State Examination (MMSE) did not statistically increase diagnostic efficiency. &lt;i&gt;Conclusion:&lt;\/i&gt; CLOX, either alone or in combination with MMSE, is not a useful screening test for MCI in a clinical setting.<\/jats:p>","DOI":"10.1159\/000315515","type":"journal-article","created":{"date-parts":[[2010,7,5]],"date-time":"2010-07-05T06:58:29Z","timestamp":1278313109000},"page":"20-27","source":"Crossref","is-referenced-by-count":22,"title":["Diagnostic Performance of an Executive Clock Drawing Task (CLOX) as a Screening Test for Mild Cognitive Impairment in Elderly Persons with Cognitive 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