{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:39:11Z","timestamp":1789587551342,"version":"build-2803163510"},"reference-count":7,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2010,12,15]],"date-time":"2010-12-15T00:00:00Z","timestamp":1292371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,12,15]],"date-time":"2010-12-15T00:00:00Z","timestamp":1292371200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Persistent trophoblast is a recognised complication of salpingostomy for the treatment of ectopic pregnancy, with reported rates of 3\u201320%; hence, women are advised to have serum human chorionic gonadotrophin (hCG) levels monitored post-operatively. Although much less common, there are also reports of disseminated trophoblastic peritoneal implants after laparoscopic salpingectomy. The aim of this study was to assess whether monitoring of post-operative serum hCG levels is necessary in women undergoing salpingectomy, where intra-operative spillage of trophoblast is thought to have occurred. &lt;i&gt;Methods:&lt;\/i&gt; This was a retrospective study of women who underwent serum hCG follow-up after salpingectomy. Serum hCG levels were monitored if: (1) the ectopic pregnancy was found to be ruptured; (2) there was a significant haemoperitoneum (&gt;500 ml); (3) there was thought to be spillage of trophoblast at the time of salpingectomy or (4) a tubal miscarriage was diagnosed. Serum hCG levels were taken at days 1\u20132, days 3\u20134, days 6\u20138 or days 13\u201315 post-surgery. Women were followed up until the serum hCG level was &lt;15 IU\/l. Persistent trophoblast was defined as a failure of the serum hCG level to decrease spontaneously after surgery. &lt;i&gt;Results:&lt;\/i&gt; 105 women underwent serum hCG follow-up after a laparoscopy for a tubal ectopic pregnancy. Of these women, 92 had a laparoscopic salpingectomy and 13 were diagnosed with a tubal miscarriage at the time of laparoscopy. In all women the serum hCG decreased spontaneously. &lt;i&gt;Conclusion:&lt;\/i&gt; It does not appear necessary to routinely monitor serum hCG levels post-operatively in women diagnosed with tubal miscarriages, in those undergoing salpingectomy for a ruptured ectopic pregnancy or in cases of salpingectomy, where there is thought to be spillage of trophoblast.<\/jats:p>","DOI":"10.1159\/000318221","type":"journal-article","created":{"date-parts":[[2011,6,15]],"date-time":"2011-06-15T15:11:53Z","timestamp":1308150713000},"page":"225-228","source":"Crossref","is-referenced-by-count":11,"title":["Is Serum Human Chorionic Gonadotrophin Follow-Up Necessary after Suspected Spillage of Trophoblast at the Time of Laparoscopic Surgery for Ectopic Pregnancy?"],"prefix":"10.1159","volume":"71","author":[{"given":"Shabana A.","family":"Bora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anneleen","family":"Daemen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Timmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Bourne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,12,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093%2Fhumrep%2Fdeh770"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1080%2F00313020601137367"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1089%2Flps.1993.3.157"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-2115%2800%2900385-7"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0046-8177%2898%2990231-3"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0412.2002.811110.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F01.AOG.0000142712.80407.fd"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/318221","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/318221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:34:01Z","timestamp":1745436841000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000318221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,15]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,6,1]]},"published-print":{"date-parts":[[2011,6,16]]}},"URL":"https:\/\/doi.org\/10.1159\/000318221","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,15]]}}}