{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:29:42Z","timestamp":1792650582479,"version":"4.5.0"},"reference-count":15,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T00:00:00Z","timestamp":1286928000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T00:00:00Z","timestamp":1286928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2011]]},"abstract":"<i>Background:<\/i> Proximal lung tumors, though not discernable by means of transthoracic ultrasound (US), may cause varying degrees of pulmonary collapse and postobstructive pneumonitis which may give rise to a \u2018drowned lung\u2019 appearance on chest computed tomography (CT) and US. The diagnostic yield for malignancy of US-assisted transthoracic fine-needle aspiration (FNA) of these areas of drowned lung is unknown. <i>Objectives:<\/i> We aimed to explore the feasibility of US-assisted FNA in this setting by prospectively investigating its diagnostic yield and safety. <i>Methods:<\/i> We enrolled 31 patients (aged 59.4 \u00b1 9.7 years, 17 males) with central tumors and secondary drowned lung on CT scan. A respiratory physician performed transthoracic US to identify the target drowned lung tissue. Three US-assisted superficial FNA passes (\u226420 mm from the pleura) were followed by 3 deeper FNA passes (>20 mm) aimed in the direction of a visible or approximated central mass. Rapid on-site evaluation of specimens was used. <i>Results:<\/i> Superficial FNA was diagnostic in 11 patients (35.5%), whereas deeper FNA was diagnostic in 23 patients (74.2%, p = 0.002). Deeper FNA confirmed malignancy in all cases with diagnostic superficial FNA. We observed no pneumothoraces or major hemorrhage. All patients were ultimately diagnosed with malignancy (bronchogenic carcinoma, n = 30; lymphoma, n = 1). <i>Conclusions:<\/i> US-assisted FNA of drowned lung has an acceptable diagnostic yield and is safe.<\/jats:p>","DOI":"10.1159\/000319576","type":"journal-article","created":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T10:29:29Z","timestamp":1286965769000},"page":"26-31","source":"Crossref","is-referenced-by-count":19,"title":["The Diagnostic Yield and Safety of Ultrasound-Assisted Transthoracic Fine-Needle Aspiration of Drowned Lung"],"prefix":"10.1159","volume":"81","author":[{"given":"Coenraad F.N.","family":"Koegelenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris T.","family":"Bolliger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvis M.","family":"Irusen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen A.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercia","family":"Louw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel T.","family":"Schubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas H.","family":"Diacon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,10,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.122.5.1759"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mcp.0000166591.03042.1f"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ccm.2006.01.003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1440-1843.2004.00599.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000080638"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.00077706"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.00128108"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0149-936X%2885%2990007-4"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.07-2800"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.07-1357"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000277931"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2820001201%2989%3A11%2B%3C2461%3A%3AAID-CNCR23%3E3.0.CO%3B2-L"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136%2Fjcp.50.7.566"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.108.1.131"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.08-0978"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/319576","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/319576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:42:37Z","timestamp":1745437357000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000319576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,13]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,12,1]]},"published-print":{"date-parts":[[2010,12,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000319576","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,13]]}}}