{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:38:13Z","timestamp":1745469493033,"version":"3.40.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2010,8,6]],"date-time":"2010-08-06T00:00:00Z","timestamp":1281052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,8,6]],"date-time":"2010-08-06T00:00:00Z","timestamp":1281052800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron Clin Pract"],"abstract":"<i>Aims:<\/i> To evaluate the role of the quantitative vascularization index (VI) as a measure of the completeness of percutaneous ethanol injection therapy (PEIT). <i>Methods:<\/i> A total of 37 dialysis patients with secondary hyperparathyroidism refractory to medical therapy received PEIT. We analyzed the role of a quantitative marker of parathyroid adenoma activity, i.e. VI, flow index and vascular flow index as measured by 3-dimensional Doppler ultrasound with a 3-dimensional histogram software, for all patients before treatment and at 1 month and 6 months after PEIT. <i>Results:<\/i> Serum intact parathyroid hormone (i-PTH) level showed a strong positive correlation with the VI both before (p < 0.001) and after (p < 0.001) PEIT. There was no correlation between i-PTH level and the volume of the gland either before (p = 0.697) or after (p = 0.564) PEIT. One month after PEIT, 20 patients (group 1) reached the target of i-PTH \u2264300 pg\/ml and 17 patients (group 2) did not. Group 2 patients had significantly greater VI and i-PTH prior to PEIT than group 1 patients (42.23 \u00b1 8.38 vs. 14.95 \u00b1 8.07, p <0.001 and 1,447 \u00b1 243 vs. 859 \u00b1 231, p < 0.001 respectively). <i>Conclusion:<\/i> A higher VI indicates a higher i-PTH, and the VI may be a reliable predictor of the completeness of PEIT.<\/jats:p>","DOI":"10.1159\/000319659","type":"journal-article","created":{"date-parts":[[2010,8,6]],"date-time":"2010-08-06T07:29:12Z","timestamp":1281079752000},"page":"c120-c126","source":"Crossref","is-referenced-by-count":3,"title":["Role of the Parathyroid Gland Vascularization Index in Predicting Percutaneous Ethanol Injection Efficacy in Refractory Uremic Hyperparathyroidism"],"prefix":"10.1159","volume":"117","author":[{"given":"Han-Hsiang","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo-Cheng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Jui","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Jen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,8,6]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1038%2Fsj.ki.5001595"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1056%2FNEJM199507203330307"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.1038%2Fsj.ki.5001597"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1111%2Fj.1744-9987.2005.00301.x"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1016%2FS0272-6386%2899%2970146-0"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1016%2FS0272-6386%2803%2900910-7"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1111%2Fj.1774-9987.2005.00214.x"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.1046%2Fj.1523-1755.63.s85.24.x"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.1093%2Fndt%2Fgfg1015"},{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.1093%2Fndt%2Fgfl620"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1016%2FS0301-5629%2802%2900486-6"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.1016%2FS0301-5629%2803%2900992-X"},{"doi-asserted-by":"publisher","key":"ref13","DOI":"10.1093%2Fhumrep%2F17.9.2484"},{"doi-asserted-by":"publisher","key":"ref14","DOI":"10.1093%2Fndt%2Fgfg1041"},{"doi-asserted-by":"publisher","key":"ref15","DOI":"10.1093%2Fndt%2F13.12.3111"},{"doi-asserted-by":"publisher","key":"ref16","DOI":"10.1038%2Fki.1994.373"},{"doi-asserted-by":"publisher","key":"ref17","DOI":"10.1159%2F000086222"},{"doi-asserted-by":"publisher","key":"ref18","DOI":"10.1093%2Fndt%2Fgfg1009"}],"container-title":["Nephron Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/319659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/319659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:43:42Z","timestamp":1745437422000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000319659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,6]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000319659","archive":["Portico"],"relation":{},"ISSN":["1660-2110"],"issn-type":[{"type":"electronic","value":"1660-2110"}],"subject":[],"published":{"date-parts":[[2010,8,6]]}}}