{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:32:09Z","timestamp":1770823929216,"version":"3.50.1"},"reference-count":7,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2010,12,13]],"date-time":"2010-12-13T00:00:00Z","timestamp":1292198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,12,13]],"date-time":"2010-12-13T00:00:00Z","timestamp":1292198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To report a case of primary yolk sac (endodermal sinus) tumour (YST) of the vulva which is very rare and to highlight some unusual features of this tumour in the vulva. &lt;i&gt;Clinical Presentation and Intervention:&lt;\/i&gt; A 23-year-old woman presented with a 1-month swelling in the right labium majus that was non-tender and rapidly increasing in size. The mass was excised; it grossly measured 6 \u00d7 5 \u00d7 3 cm and was firm with a grey white cut surface. Microscopically it showed features of YST. The patient returned to the clinic only after 2 months with a recurrent mass of almost the same size with ipsilateral lymphadenopathy. At that time serum \u03b1-fetoprotein showed only a mild increase (13.4 \u00b5g\/l, normal: 0\u201310 \u00b5g\/l). Further management was not possible as she decided to return to her native country for treatment. A literature review shows that local excision with lymphadenectomy followed by cisplatin-based chemotherapy is the best mode of treatment for primary YST of the vulva. &lt;i&gt;Conclusion:&lt;\/i&gt; This case is presented for its rarity and to highlight the fact that serum \u03b1-fetoprotein estimation may not aid in the primary diagnosis or detection of recurrence in patients on follow-up for YST arising in the vulva unlike those seen in the gonads.<\/jats:p>","DOI":"10.1159\/000319917","type":"journal-article","created":{"date-parts":[[2010,12,14]],"date-time":"2010-12-14T11:55:59Z","timestamp":1292327759000},"page":"90-92","source":"Crossref","is-referenced-by-count":7,"title":["Primary Yolk Sac (Endodermal Sinus) Tumour of the Vulva: A Case Report"],"prefix":"10.1159","volume":"20","author":[{"given":"Nagesh Babu","family":"Subrahmanya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surendra Nayak","family":"Kapadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.A.","family":"Junaid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,12,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1048-891X.2004.14540.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ygyno.2004.12.054"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819880801%2962%3A3%3C620%3A%3AAID-CNCR2820620330%3E3.0.CO%3B2-P"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1006%2Fgyno.1997.4759"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3109%2F08880019809167228"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819800715%2946%3A2%3C380%3A%3AAID-CNCR2820460228%3E3.0.CO%3B2-U"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%28197612%2938%3A6%3C2404%3A%3AAID-CNCR2820380629%3E3.0.CO%3B2-3"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/319917","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/319917","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:46:30Z","timestamp":1745437590000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000319917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,13]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,12,1]]},"published-print":{"date-parts":[[2010,12,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000319917","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,13]]}}}