{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T17:30:53Z","timestamp":1788370253329,"version":"build-2803163510"},"reference-count":28,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Objectives:&lt;\/i&gt; The purpose of this study was to examine developmental enamel defects and dental caries in very low birth weight adolescents with high risk (HR-VLBW) and low risk (LR-VLBW) compared to full-term (term) adolescents. &lt;i&gt;Methods:&lt;\/i&gt; The sample consisted of 224 subjects (80 HR-VLBW, 59 LR-VLBW, 85 term adolescents) recruited from an ongoing longitudinal study. Sociodemographic and medical information was available from birth. Dental examination of the adolescent at the 14-year visit included: enamel defects (opacity and hypoplasia); decayed, missing, filled teeth of incisors and molars (DMFT-IM) and of overall permanent teeth (DMFT); Simplified Oral Hygiene Index for debris\/calculus on teeth, and sealant presence. A caregiver questionnaire completed simultaneously assessed dental behavior, access, insurance status and prevention factors. Hierarchical analysis utilized the zero-inflated negative binomial model and zero-inflated Poisson model. &lt;i&gt;Results:&lt;\/i&gt; The zero-inflated negative binomial model controlling for sociodemographic variables indicated that the LR-VLBW group had an estimated 75% increase (p &lt; 0.05) in number of demarcated opacities in the incisors and first molar teeth compared to the term group. Hierarchical modeling indicated that demarcated opacities were a significant predictor of DMFT-IM after control for relevant covariates. The term adolescents had significantly increased DMFT-IM and DMFT scores compared to the LR-VLBW adolescents. &lt;i&gt;Conclusion:&lt;\/i&gt; LR-VLBW was a significant risk factor for increased enamel defects in the permanent incisors and first molars. Term children had increased caries compared to the LR-VLBW group. The effect of birth group and enamel defects on caries has to be investigated longitudinally from birth.<\/jats:p>","DOI":"10.1159\/000320160","type":"journal-article","created":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T07:08:08Z","timestamp":1288076888000},"page":"509-518","source":"Crossref","is-referenced-by-count":53,"title":["Dental Caries and Enamel Defects in Very Low Birth Weight Adolescents"],"prefix":"10.1159","volume":"44","author":[{"given":"S.","family":"Nelson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Albert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Lombardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Wishnek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Asaad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.L.","family":"Kirchner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.T.","family":"Singer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,10,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0714.2000.290806.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.2009.00480.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177%2F154405910508400310"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fsim.1088"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1752-7325.1996.tb02400.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000262006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1590%2FS1806-83242006000400013"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.294.3.318"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0722.2001.00047.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.jp.7211580"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.107.1.e1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0021-9924%2802%2900085-0"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.2004.00155.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000262130"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2F1467-9884.00263"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.2006-2089D"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159%2F000073400"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199904013401311"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3476%2880%2980341-6"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159%2F000072162"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159%2F000093188"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093%2Foxfordjournals.epirev.a017999"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.2006.00345.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-3016.2007.00782_1.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1834-7819.1997.tb00102.x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.112.5.e359"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.100.6.987"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.2004-0221"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/320160","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/320160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:48:33Z","timestamp":1745437713000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000320160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":28,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2011,1,1]]},"published-print":{"date-parts":[[2011,1,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000320160","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}