{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T06:29:41Z","timestamp":1766557781094,"version":"3.40.4"},"reference-count":19,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2010]]},"abstract":"<i>Aim:<\/i> The efficacy of early maternal caries prevention in children was evaluated. <i>Methods:<\/i> First-time mothers selected on the basis of a high level of salivary mutans streptococci (MS) and mothers excluded at screening due to a low level of MS (\u2018low\u2019) were recalled when their children were 11 years old. The salivary MS level was determined in the mothers. Their children were examined for salivary MS and lesion prevalence (decayed and filled surfaces, DFS) at the ages of 11 and 15 years. <i>Results:<\/i> More \u2018high control\u2019 mothers displayed \u226710<sup>6<\/sup> MS than the \u2018high interventional\u2019 and \u2018low control\u2019 mothers and, vice versa, more \u2018interventional\u2019 and \u2019low control\u2019 mothers had MS counts of <3 \u00d7 10<sup>5<\/sup> than \u2019high control\u2019 mothers. More of \u2018interventional\u2019 and \u2019low control\u2019 children had <10<sup>5<\/sup> MS\/ml as compared with the \u2019high control\u2019 children. All the \u2019high control\u2019 children had detectable MS. MS were undetected in 5 \u2018interventional\u2019 and 5 \u2019low control\u2019 children at 15 years. Significantly fewer \u2019high control\u2019 than \u2018interventional\u2019 and \u2019low control\u2019 children were caries free at 11 and 15 years of age. Non-MS-colonised children at 3 years of age, irrespective of group identity, displayed statistically lower MS counts and less DFS at 15 years than those colonised at 3 years of age. Children with clinical caries\/fillings at 15 years had had a significantly higher level of MS at 11 years of age than those without clinical caries\/fillings. <i>Conclusion:<\/i> The clinical trial, focusing on the mothers, resulted in long-term benefits for their children. Children colonised by MS at an early stage developed more caries than those colonised at a later stage.<\/jats:p>","DOI":"10.1159\/000320168","type":"journal-article","created":{"date-parts":[[2010,9,13]],"date-time":"2010-09-13T10:01:01Z","timestamp":1284372061000},"page":"453-458","source":"Crossref","is-referenced-by-count":24,"title":["Mutans Streptococci and Caries Prevalence in Children after Early Maternal Caries Prevention: A Follow-Up at Eleven and Fifteen Years of Age"],"prefix":"10.1159","volume":"44","author":[{"given":"B.","family":"K\u00f6hler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Andr\u00e9en","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2010,9,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.2005.00232.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2F0003-9969%2891%2990036-T"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159%2F000063922"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2F0003-9969%2873%2990109-X"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs007840050059"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0003-9969%2802%2900017-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345000790111201"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0003-9969%2894%2990023-X"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2F0003-9969%2884%2990086-4"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1399-302X.1988.tb00598.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2F0003-9969%2883%2990151-6"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159%2F000261005"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1834-7819.2007.tb00471.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2458-8-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186%2F1472-6831-5-1"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1752-7325.1980.tb01845.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-263X.2006.00720.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159%2F000094280"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159%2F000262041"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/320168","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/320168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:48:36Z","timestamp":1745437716000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000320168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2010,11,1]]},"published-print":{"date-parts":[[2010,11,16]]}},"URL":"https:\/\/doi.org\/10.1159\/000320168","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"type":"print","value":"0008-6568"},{"type":"electronic","value":"1421-976X"}],"subject":[],"published":{"date-parts":[[2010]]}}}