{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:31:43Z","timestamp":1790188303091,"version":"4.1.0"},"reference-count":9,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2010,10,28]],"date-time":"2010-10-28T00:00:00Z","timestamp":1288224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,10,28]],"date-time":"2010-10-28T00:00:00Z","timestamp":1288224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiol Neurotol"],"published-print":{"date-parts":[[2011]]},"abstract":"<i>Objective:<\/i> Our purposes were to characterize hyperventilation-induced nystagmus (HVIN) in patients with unilateral vestibular neuritis (VN) through follow-up examinations and to determine the effects of hyperventilation on vestibular imbalance in patients with VN. <i>Materials and Methods:<\/i> The horizontal eye movements in 35 patients with acute VN were recorded. The eye movements were analyzed and the maximum value of slow-phase eye velocity (SPV) was obtained during and after hyperventilation. Nineteen of 35 patients underwent follow-up examinations around 7 weeks later. When spontaneous nystagmus was present, the SPV of spontaneous nystagmus was subtracted from that of HVIN. A maximum SPV of HVIN of \u22674\u00b0\/s was considered abnormal. The direction and SPV of HVIN were analyzed. <i>Results:<\/i> The incidence of HVIN in patients with VN was significantly higher in the acute stage (18 of 35; 51%) than the follow-up stage (4 of 19; 21%). The direction of HVIN present in the follow-up stage was entirely towards the contralesional side (contralesional HVIN). However, the direction of HVIN in the acute stage was mixed, towards the contralesional side (10 of 35; 28%) and towards the ipsilesional side (8 of 35; 23%). The SPVs (49 \u00b1 56\u00b0\/s) of ipsilesional HVIN were significantly greater than the contralesional HVIN in the acute stage (8 \u00b1 3\u00b0\/s). Robust nystagmus (SPV \u226725\u00b0\/s) was entirely ipsilesional HVIN, which was observed only in the acute stage. <i>Conclusions:<\/i> Our findings indicate that hyperventilation can result in aggravation of vestibular imbalance in the acute and follow-up stages in different ways. Hyperventilation resulted in contralesional HVIN in both the acute and follow-up stages, each in approximately a fourth of the patients, which suggests a disruption of central static compensatory mechanisms. However, ipsilesional HVIN was elicited only in the acute stage (in approximately a fourth of the patients). About half of the patients with ipsilesional HVIN showed robust responses, which is a characteristic finding, suggesting a transient intense increase in vestibular activity on the lesional side.<\/jats:p>","DOI":"10.1159\/000320841","type":"journal-article","created":{"date-parts":[[2010,10,28]],"date-time":"2010-10-28T07:38:53Z","timestamp":1288251533000},"page":"248-253","source":"Crossref","is-referenced-by-count":11,"title":["Hyperventilation-Induced Nystagmus in Patients with Vestibular Neuritis in the Acute and Follow-Up Stages"],"prefix":"10.1159","volume":"16","author":[{"given":"Hong Ju","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Eun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeo Jin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mun Su","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Myung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Ra","family":"Na","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,10,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00005537-199804000-00027"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.52.9.1107"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1212%2F01.wnl.0000271378.54381.6a"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.33.6.723"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1748-1716.1965.tb03234.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3342%2Fceo.2009.2.3.145"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2FMAO.0b013e3181b0ff1b"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2310%2F7070.2002.10796"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F00129492-200211000-00031"}],"container-title":["Audiology and Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/320841","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/320841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:54:33Z","timestamp":1745438073000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000320841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,28]]},"references-count":9,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,5,1]]},"published-print":{"date-parts":[[2011,5,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000320841","archive":["Portico"],"relation":{},"ISSN":["1420-3030","1421-9700"],"issn-type":[{"value":"1420-3030","type":"print"},{"value":"1421-9700","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,28]]}}}