{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:40:07Z","timestamp":1790260807688,"version":"4.1.0"},"reference-count":21,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy"],"published-print":{"date-parts":[[2010]]},"abstract":"<i>Background:<\/i> This study was conducted to determine the antimicrobial susceptibility patterns among common pathogens in the intensive care unit (ICU) of a university hospital in Iran between 2006 and 2009. <i>Methods:<\/i> The isolates cultured in appropriate media and antimicrobial susceptibility were determined by disk diffusion tests according to the guidelines of the Clinical and Laboratory Standards Institute. <i>Results:<\/i> A total of 606 isolates were recovered from respiratory (70.63%), urine (20.13%), blood (4.95%) and wound (1.82%) specimens of 456 patients. The most common isolates were <i>Acinetobacter baumannii<\/i> (22.4%), <i>Pseudomonas aeruginosa<\/i> (20.6%), <i>Staphylococcus aureus<\/i> (11.1%), <i>Escherichia coli<\/i> (8.3%) and <i>Klebsiella pneumoniae<\/i> (4.8%). Less than 7% of <i>A. baumannii <\/i>isolates were susceptible to aminoglycosides, ceftazidime, cefotaxime, imipenem, cefepime and ciprofloxacin. None was susceptible to piperacillin and piperacillin-tazobactam. The susceptibility rates of <i>P. aeruginosa<\/i> to ciprofloxacin, gentamicin and piperacillin-tazobactam were 13.6, 17.4 and 33.3%, respectively. Methicillin-resistant <i>S. aureus<\/i> made up 96.2% of <i>S. aureus<\/i> isolates and was 100% susceptible to vancomycin and 51.9% susceptible to trimethoprim-sulfamethoxazole. <i>Conclusion:<\/i> Due to the high antimicrobial resistance in the ICU, we must focus on both a wiser use of antimicrobials and the prevention of infection.<\/jats:p>","DOI":"10.1159\/000321032","type":"journal-article","created":{"date-parts":[[2010,11,23]],"date-time":"2010-11-23T04:20:18Z","timestamp":1290486018000},"page":"478-484","source":"Crossref","is-referenced-by-count":23,"title":["Surveillance of Antimicrobial Susceptibility among Bacterial Isolates from Intensive Care Unit Patients of a Tertiary-Care University Hospital in Iran: 2006\u20132009"],"prefix":"10.1159","volume":"56","author":[{"given":"Zohreh","family":"Mohammadtaheri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Pourpaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Forouzan","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocsanna","family":"Namdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad-Reza","family":"Masjedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,11,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1128%2FJCM.39.8.2823-2828.2001"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F00003246-200104001-00002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053%2Fic.1999.v27.a98878"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.diagmicrobio.2005.12.009"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ijantimicag.2006.10.017"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.118.1.146"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.115.2.462"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128%2FJCM.01284-07"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2334-6-155"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000141500"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007%2Fs100960100455"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ijantimicag.2003.12.019"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1128%2FAAC.01538-07"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1086%2F321893"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186%2F1476-0711-5-2"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1128%2FJCM.41.7.3339-3343.2003"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1300%2FJ100v05n03_05"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159%2F000198698"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2FS1473-3099%2806%2970689-2"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.diagmicrobio.2007.10.010"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159%2F000224656"}],"container-title":["Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/321032","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/321032","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/321032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:56:12Z","timestamp":1745420172000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000321032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":21,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2010,12,1]]},"published-print":{"date-parts":[[2010,12,16]]}},"URL":"https:\/\/doi.org\/10.1159\/000321032","archive":["Portico"],"relation":{},"ISSN":["0009-3157","1421-9794"],"issn-type":[{"value":"0009-3157","type":"print"},{"value":"1421-9794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}