{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T12:18:59Z","timestamp":1790943539089,"version":"4.1.0"},"reference-count":33,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To study which cognitive profiles of incipient dementia strongest predict the conversion to Alzheimer\u2019s disease (AD) and mixed dementia (MD)\/vascular dementia (VaD). &lt;i&gt;Methods:&lt;\/i&gt; 260 subjects with mild cognitive impairment (MCI) were included in the study and 209 (79%) were followed up after 2 years. At baseline, the subjects were assessed with a neuropsychological battery covering the cognitive domains speed\/attention, memory, visuospatial, language and executive functions. &lt;i&gt;Results:&lt;\/i&gt; After 2 years, 9 subjects were considered normal, 148 had stationary MCI and 47 (23%) had converted to dementia. Twenty subjects were diagnosed with AD, 15 with MD and 9 with VaD. The others were 2 with unspecified dementias and 1 with primary progressive aphasia. Dementia converters had a high proportion of impairment in all cognitive domains. The profiles of incipient AD and MD\/VaD differed, with memory, visuospatial and language symptoms preceding AD, and executive and speed\/attention symptoms preceding MD\/VaD. &lt;i&gt;Conclusions:&lt;\/i&gt; The risk of converting to dementia is increased when domains in addition to memory are impaired. The incipient AD and MD\/VaD profiles differed quite clearly. Considering that the vascular group consisted of a majority of patients with MD, the differences are convincing \u2013 vascular disease seems to have an essential impact on cognition.<\/jats:p>","DOI":"10.1159\/000321352","type":"journal-article","created":{"date-parts":[[2010,10,25]],"date-time":"2010-10-25T07:43:19Z","timestamp":1287992599000},"page":"403-410","source":"Crossref","is-referenced-by-count":33,"title":["Cognitive Profiles of Incipient Dementia in the Goteborg MCI 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