{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T10:46:25Z","timestamp":1792320385435,"version":"4.4.0"},"reference-count":20,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2010,12,13]],"date-time":"2010-12-13T00:00:00Z","timestamp":1292198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2010,12,13]],"date-time":"2010-12-13T00:00:00Z","timestamp":1292198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; This study assessed the diagnostic yield of capsule endoscopy (CE) and its impact on patients with obscure gastrointestinal bleeding (OGIB). &lt;i&gt;Subjects and Methods:&lt;\/i&gt; Between May 2007 and May 2009, 63 patients with OGIB (overt bleeding: 25, and occult blood loss with chronic ferropenic anemia: 38) and normal upper and lower endoscopy were studied by CE. Demographic characteristics, prior diagnostic tests, CE findings, therapeutic interventions, medical treatment and clinical outcomes following CE were evaluated. &lt;i&gt;Results:&lt;\/i&gt; The overall diagnostic yield was 44.44% of patients and included findings of angiectasia in 11 (17.46%) patients, nonsteroidal anti-inflammatory drugs enteropathy in 6 (9.52%) patients, celiac disease in 3 (4.76%) patients, tumors in 2 (3.17%) patients, and a variety of other diagnoses ranging from varices to ulcers (due to congenital afibrinogenemia and amyloidosis). The diagnostic yield was notably higher in overt bleeders (15\/25, 60%) compared to occult bleeders (13\/38, 34.21%; p = 0.044), and in patients with overt bleeding who had CE within the first 10 days (14\/16, 87.5%) after the bleeding episode in comparison to overt bleeders who underwent CE &gt;10 days after the bleeding episode (2\/16, 11.1%; p &lt; 0.0001). During follow-up (11.8 \u00b1 7 months), CE findings led to specific therapy that resolved the underlying disease or improved the clinical condition in 45 of 63 patients, thus having a positive clinical impact of 71.43%. &lt;i&gt;Conclusion:&lt;\/i&gt; CE has a high diagnostic yield and a positive influence on clinical management in a significant proportion of patients with OGIB. These data further support the role of CE in routine clinical practice.<\/jats:p>","DOI":"10.1159\/000322071","type":"journal-article","created":{"date-parts":[[2010,12,14]],"date-time":"2010-12-14T11:55:59Z","timestamp":1292327759000},"page":"60-65","source":"Crossref","is-referenced-by-count":20,"title":["Diagnostic Yield and Clinical Impact of Capsule Endoscopy in Obscure Gastrointestinal Bleeding during Routine Clinical Practice: A Single-Center Experience"],"prefix":"10.1159","volume":"20","author":[{"given":"Panagiotis","family":"Katsinelos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grigoris","family":"Chatzimavroudis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotiris","family":"Terzoudis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Patsis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kostas","family":"Fasoulas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taxiarchis","family":"Katsinelos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Kokonis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Zavos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Themistoklis","family":"Vasiliadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannis","family":"Kountouras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2010,12,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.bpg.2005.08.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mcg.0000225616.79223.75"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2006-944874"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10620-006-9605-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.giec.2003.10.004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2002-33446"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053%2Fgast.2002.35988"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.gastro.2003.11.057"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2004-826034"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1572-0241.2006.00941.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.gie.2005.06.049"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00042737-200608000-00014"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10620-006-9610-6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080%2F00365520500335159"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2804%2902226-6"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2F00042737-200409000-00019"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.gastro.2007.06.007"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2005-870319"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1572-0241.2007.01238.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1572-0241.2005.41069.x"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:07:05Z","timestamp":1745435225000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000322071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,13]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,12,1]]},"published-print":{"date-parts":[[2010,12,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000322071","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,13]]}}}