{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:21:48Z","timestamp":1773008508305,"version":"3.50.1"},"reference-count":18,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; While subcorneal pustular dermatosis-type IgA pemphigus shows subcorneal pustules, intra-epidermal neutrophilic dermatosis (IEN)-type IgA pemphigus is characterised by pustule formation throughout the entire epidermis. &lt;i&gt;Objective:&lt;\/i&gt; We analysed an unusual case of IEN-type IgA pemphigus showing subcorneal pustules. &lt;i&gt;Methods:&lt;\/i&gt; Indirect immunofluorescence, immunoblot analysis, auto-antibody-specific ELISAs, and double-labelling immuno-electron microscopy were performed. &lt;i&gt;Results:&lt;\/i&gt; IgA antibodies bound to the surface of keratinocytes distributed throughout the epidermis were detected by indirect immunofluorescence. IgA from the patient\u2019s serum failed to react with COS-7 cells expressing desmocollins (Dsc) 1, 2 or 3. IgG or IgA antibodies against desmogleins 1 and 3 were also found to be absent by ELISA. Double-labelling immuno-electron microscopy using an anti-Dsc monoclonal antibody showed localisation in the desmosomes, while IgA from the patient\u2019s serum was found in non-desmosomal regions. &lt;i&gt;Conclusion:&lt;\/i&gt; The patient in the present study most likely suffers from IEN-type IgA pemphigus.<\/jats:p>","DOI":"10.1159\/000322839","type":"journal-article","created":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T10:52:09Z","timestamp":1294743129000},"page":"15-19","source":"Crossref","is-referenced-by-count":4,"title":["A Unique Case of Intra-Epidermal Neutrophilic Dermatosis-Type IgA Pemphigus Presenting with Subcorneal Pustules"],"prefix":"10.1159","volume":"222","author":[{"given":"Koji","family":"Iida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohiko","family":"Sueki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bungo","family":"Ohyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norito","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2899%2970145-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM198512263132606"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.127.2.221"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1983.tb07683.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.123.8.1062"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0923-1811%2895%2900449-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2F1523-1747.ep12319025"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2230.2004.01436.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2003.119"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2F0190-9622%2890%2970125-2"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000247480"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2230.2002.01061.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0625.2000.009003224.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2004.05995.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2006.07226.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0923-1811%2899%2900016-X"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.129.5.605"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0625.2005.00367.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322839","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322839","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:15:16Z","timestamp":1745435716000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000322839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2011,2,1]]},"published-print":{"date-parts":[[2011,2,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000322839","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}