{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T15:33:40Z","timestamp":1784993620657,"version":"3.55.0"},"reference-count":6,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>This study presents 12 patients (7 women and 5 men) with vitamin B&lt;sub&gt;12&lt;\/sub&gt;-responsive pancytopenia who had discordant laboratory findings and were misdiagnosed as having myelodysplastic syndrome (MDS). The median hemoglobin level was 6.5 g\/dl, and the leukocyte and platelet counts were 2.85 \u00d7 10&lt;sup&gt;9&lt;\/sup&gt;\/l and 55.5 \u00d7 10&lt;sup&gt;9&lt;\/sup&gt;\/l, respectively. The median serum lactate dehydrogenase level was high (3,204.5 IU\/l). The serum vitamin B&lt;sub&gt;12&lt;\/sub&gt; levels were within normal limits at the initial evaluation, but a serial follow-up of the vitamin B&lt;sub&gt;12&lt;\/sub&gt; levels revealed either fluctuations or a gradual decrease. The patients were initially diagnosed with MDS and responded rapidly to a 7-day parenteral B&lt;sub&gt;12&lt;\/sub&gt; treatment with normal complete blood counts (CBCs). We propose that patients suspected to have MDS may suffer from vitamin B&lt;sub&gt;12&lt;\/sub&gt; deficiency and that this can be revealed by a normalization of CBCs following 7 days of treatment with parental vitamin B&lt;sub&gt;12&lt;\/sub&gt;.<\/jats:p>","DOI":"10.1159\/000322941","type":"journal-article","created":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T07:56:22Z","timestamp":1295510182000},"page":"198-201","source":"Crossref","is-referenced-by-count":25,"title":["Vitamin B&lt;sub&gt;12&lt;\/sub&gt;-Responsive Pancytopenia Mimicking Myelodysplastic Syndrome"],"prefix":"10.1159","volume":"125","author":[{"given":"Myungshin","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Eun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joonhong","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihyang","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Sik","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoo-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Je","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Ki","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggoo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok-Goo","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,1,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.blre.2006.02.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjmed.2006.02.001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2257.2006.00755.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0609.2005.00563.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.0954-6820.1967.tb07262.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1517%2F14656560903456053"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322941","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322941","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/322941","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:15:59Z","timestamp":1745435759000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000322941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,5,1]]},"published-print":{"date-parts":[[2011,5,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000322941","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}