{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:12:11Z","timestamp":1790827931414,"version":"4.1.0"},"reference-count":6,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res Paediatr"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background\/Aims:&lt;\/i&gt; It is not exactly known how many children develop the triphasic response (diabetes insipidus (DI)\/hyponatremia\/DI) immediately after surgery for childhood craniopharyngioma; neither is it known which factors predict this. We studied the occurrence of the triphasic response after primary surgery for craniopharyngioma in children, and aimed to identify possible predictors. &lt;i&gt;Methods:&lt;\/i&gt; Patients &lt;18 years old who had undergone a primary craniopharyngioma resection between January 1990 and February 2010 in either of the 2 academic centers in Amsterdam were studied retrospectively. &lt;i&gt;Results:&lt;\/i&gt; Twenty-one patients (5 males) fulfilled the inclusion criteria. Median age at surgery was 9.1 (range: 4.0\u201315.1) years. Six patients developed a triphasic response (29%). Of all factors, only the duration of surgery was found to be a predictor of a triphasic response: 8.5 (6.0\u201311.0) versus 4.6 (3.5\u201311.5) h in patients who did not develop a triphasic response (p = 0.03). &lt;i&gt;Conclusion:&lt;\/i&gt; After primary surgery for a craniopharyngioma, a considerable number of patients develop a triphasic response in the regulation of the sodium and water balance. This is predicted by (factors associated with) a longer duration of surgery. Other predictors could not be identified, which may be due to the small sample size.<\/jats:p>","DOI":"10.1159\/000324115","type":"journal-article","created":{"date-parts":[[2011,7,14]],"date-time":"2011-07-14T06:36:15Z","timestamp":1310625375000},"page":"22-26","source":"Crossref","is-referenced-by-count":41,"title":["Frequent Occurrence of the Triphasic Response (Diabetes Insipidus\/Hyponatremia\/Diabetes Insipidus) after Surgery for Craniopharyngioma in Childhood"],"prefix":"10.1159","volume":"76","author":[{"given":"Martijn J.J.","family":"Finken","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitash","family":"Zwaveling-Soonawala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie J.E.","family":"Walenkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Vulsma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.S. Paul","family":"van Trotsenburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joost","family":"Rotteveel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,6,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2265.1999.00666.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3171%2F2008.9.JNS08191"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2Fs003810050224"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1203%2F00006450-200003000-00006"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.82.2.107"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.57.11.837"}],"container-title":["Hormone Research in Paediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/324115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/324115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:27:58Z","timestamp":1745436478000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000324115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2011,7,1]]},"published-print":{"date-parts":[[2011,7,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000324115","archive":["Portico"],"relation":{},"ISSN":["1663-2818","1663-2826"],"issn-type":[{"value":"1663-2818","type":"print"},{"value":"1663-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}