{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T09:53:06Z","timestamp":1763200386868,"version":"3.40.4"},"reference-count":6,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To report a case of severe necrotizing ulcerative periodontitis (NUP) with a rarely associated sequestrum formation in a Nigerian HIV-positive patient. &lt;i&gt;Clinical Presentation and Intervention:&lt;\/i&gt; A 47-year-old HIV-positive male patient with no history of previous dental visits presented with a severe toothache in his lower jaw of 4 weeks\u2019 duration, which had affected his ability to chew properly. Clinical examination revealed marked gingival inflammation, moderate gingival recession and mobility of some of his lower anterior teeth: 31, 32, and 33. There was also a sequestrum present associated with the affected teeth. His CD4 cell count was 226 cells\/mm&lt;sup&gt;3&lt;\/sup&gt;. His viral load was very high (360,082 copies\/ml). The intervention included thorough debridement of the necrotic lesion and sequestrectomy. The patient responded well to treatment after 1 week of follow-up. Unfortunately, the CD4 count was not assessed further because the patient was lost to follow-up.&lt;i&gt; Conclusion:&lt;\/i&gt; This case showed that a high CD4 cell count does not necessarily prevent the occurrence of NUP in HIV-positive patients. Intervention might have enhanced a rapid positive response to the treatment within a short time.<\/jats:p>","DOI":"10.1159\/000324872","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T06:42:09Z","timestamp":1305182529000},"page":"374-376","source":"Crossref","is-referenced-by-count":13,"title":["Severe Presentation of Necrotizing Ulcerative Periodontitis in a Nigerian HIV-Positive Patient: A Case Report"],"prefix":"10.1159","volume":"20","author":[{"given":"Kehinde Adesola","family":"Umeizudike","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kofoworola Olaide","family":"Savage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Omowunmi","family":"Ayanbadejo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sulaimon Akanni","family":"Akanmu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,5,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1902%2Fannals.1999.4.1.1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1902%2Fannals.1998.3.1.62"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0714.1992.tb00995.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1601-0825.1999.tb00092.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.bdj.4807441"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1601-0825.8.s2.5.x"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/324872","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/324872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:35:20Z","timestamp":1745436920000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000324872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,5,1]]},"published-print":{"date-parts":[[2011,5,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000324872","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"type":"print","value":"1011-7571"},{"type":"electronic","value":"1423-0151"}],"subject":[],"published":{"date-parts":[[2011]]}}}