{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T23:09:07Z","timestamp":1770505747788,"version":"3.49.0"},"reference-count":37,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Preeclampsia and preterm labor often underlie preterm birth, and are associated with maternal inflammation. In preterm infants, respiratory distress syndrome (RDS) and mechanical ventilation are associated with systemic inflammation. &lt;i&gt;Objective:&lt;\/i&gt; We aimed to study whether early-onset preeclampsia or preterm labor modulate the systemic inflammation affecting preterm infants with RDS. &lt;i&gt;Methods:&lt;\/i&gt; We recruited mechanically ventilated infants with gestational ages &lt;32 weeks; 11 infants were born after early-onset preeclampsia and 25 after preterm labor. Blood was drawn during postnatal days 1\u20137, and the mean values of days 1\u20132, 3\u20134 and 5\u20136 were used. Phagocyte CD11b expression was analyzed with flow cytometry, and plasma C-reactive protein (CRP) concentrations with immunoturbidimetry. &lt;i&gt;Results:&lt;\/i&gt; As compared with infants born after preterm labor, infants born after early-onset preeclampsia had higher CD11b expression on days 1\u20136 on both neutrophils and monocytes. In addition, infants born after early-onset preeclampsia had higher CRP concentrations on days 2\u20136 (all p &lt; 0.05). &lt;i&gt;Conclusions:&lt;\/i&gt; As compared with infants born after preterm labor to mothers without preeclampsia, infants born after early-onset preeclampsia presented with a stronger postnatal systemic inflammatory reaction. Antenatal exposure to preeclampsia may induce fetal leukocyte priming and regulation of inflammation, and thereby modify postnatal inflammatory reactions and morbidity.<\/jats:p>","DOI":"10.1159\/000325159","type":"journal-article","created":{"date-parts":[[2011,6,22]],"date-time":"2011-06-22T13:57:55Z","timestamp":1308751075000},"page":"241-247","source":"Crossref","is-referenced-by-count":9,"title":["Increased Postnatal Inflammation in Mechanically Ventilated Preterm Infants Born to Mothers with Early-Onset Preeclampsia"],"prefix":"10.1159","volume":"100","author":[{"given":"Riikka","family":"Turunen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sture","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannele","family":"Laivuori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eero","family":"Kajantie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanna","family":"Siitonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heikki","family":"Repo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irmeli","family":"Nupponen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,6,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2006.06.083"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.siny.2006.02.003"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mop.0000193290.02270.30"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000209301"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9378%2898%2970272-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.1111726"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053%2Fplac.2002.0930"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1203%2F00006450-199609000-00019"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1203%2F00006450-199609000-00020"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.110.1.36"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.2005-0123"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0378-3782%2898%2900045-0"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1172%2FJCI113102"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.108.1.e12"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1203%2F01.PDR.0000148717.59861.2C"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-199509000-00003"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097%2F00004872-200310000-00002"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1385%2FIR%3A24%3A2%3A163"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3109%2F07853890009011772"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1081%2FPRG-120016792"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1067%2Fmob.2000.108082"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1177%2F1076029606291382"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199904223401603"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1152%2Fajplung.00055.2010"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1177%2F000992288402300703"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.jp.7211056"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1159%2F000119724"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1038%2Fajh.2007.87"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjhyper.2006.06.001"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ejogrb.2004.12.009"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2004.11.055"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1053%2Fplac.2001.0691"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.nut.2005.04.006"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.bbrc.2008.06.057"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1053%2Fplac.2000.0612"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1440-1754.1996.tb01537.x"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-2115%2801%2900601-7"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/325159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/325159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:50:37Z","timestamp":1745434237000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000325159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":37,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2011,9,1]]},"published-print":{"date-parts":[[2011,9,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000325159","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1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