{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:23:38Z","timestamp":1792106618169,"version":"4.4.0"},"reference-count":15,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>This case report describes polymyxin B-immobilized fiber (PMX-F) treatment of septic shock caused by pyelonephritis in a 68-year-old woman with autosomal dominant polycystic kidney disease. She was admitted for severe lower left abdominal pain, high fever (40\u00b0C) and gross hematuria. Her endotoxin and high-mobility group box-1 protein (HMGB1) levels were extremely elevated. Her blood pressure was 68\/36 mm Hg. Urinalysis revealed innumerable white blood cells (WBCs). Blood and urine cultures were positive for &lt;i&gt;Klebsiella pneumoniae&lt;\/i&gt; and &lt;i&gt;Pseudomonas aeruginosa&lt;\/i&gt;. Plain abdominal radiography showed large kidney shadows and calcium deposition. Septic shock with endotoxemia was diagnosed. Her symptoms of septic shock persisted for 3 days with antibiotics, \u03b3-globulin and dopamine. Direct hemoperfusion was performed twice with a PMX-F column. The patient\u2019s body temperature, WBC count and C-reactive protein level decreased. Her blood endotoxin level and blood HMGB1 level also decreased to an almost normal level. She was discharged on day 23 after admission.<\/jats:p>","DOI":"10.1159\/000325731","type":"journal-article","created":{"date-parts":[[2011,6,9]],"date-time":"2011-06-09T06:35:17Z","timestamp":1307601317000},"page":"139-142","source":"Crossref","is-referenced-by-count":9,"title":["Hemoperfusion Treatment in a Septic Shock Patient with Autosomal Dominant Polycystic Kidney Disease and Increased HMGB1 Protein Levels"],"prefix":"10.1159","volume":"32","author":[{"given":"Tsukasa","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Kawagoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikaru","family":"Koide","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,6,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186%2Fcc5780"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1526-0968.2003.00005.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.cca.2006.07.019"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2FMAT.0b013e3180340301"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00134-007-0691-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mat.0000248996.22865.ce"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2894%2992026-5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9610%2894%2990126-0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.cca.2006.04.016"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00134-004-2357-7"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097%2FMAT.0b013e3181640320"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080%2F028418500127345253"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2F9780470059593.ch6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000088016"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2FSHK.0b013e3181e14ca0"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/325731","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/325731","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:56:07Z","timestamp":1745434567000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000325731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":15,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,8,1]]},"published-print":{"date-parts":[[2011,8,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000325731","archive":["Portico"],"relation":{},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"value":"0253-5068","type":"print"},{"value":"1421-9735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}