{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:04:29Z","timestamp":1779375869721,"version":"3.53.1"},"reference-count":10,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Low-frequency ultrasound has been shown to be an alternative to surgical wound debridement (WD) to stimulate wound healing; however, few data are available. &lt;i&gt;Objective:&lt;\/i&gt; To compare the efficacy, tolerability and benefit of both wound treatment methods. &lt;i&gt;Methods:&lt;\/i&gt; A monocentric prospective randomized-controlled clinical study assessing patient-reported outcomes and clinical efficacy of ultrasound-assisted wound treatment (UAW) compared to WD. &lt;i&gt;Results:&lt;\/i&gt; In total, 67 patients were treated. Efficacy and tolerability were found to be good for both treatments, with 88% of UAW and 85.2% of WD patients experiencing more-than-minimal patient benefit. Quality of life improved significantly. Wound status improved and pain decreased in both groups. &lt;i&gt;Conclusion:&lt;\/i&gt; Compared to the gold standard (i.e. WD), UAW displays the same high efficacy, comparable patient benefit and improved quality of life. Both procedures are equally suitable for highly beneficial guideline-based treatment of chronic wounds.<\/jats:p>","DOI":"10.1159\/000326116","type":"journal-article","created":{"date-parts":[[2011,4,5]],"date-time":"2011-04-05T06:15:02Z","timestamp":1301984102000},"page":"244-249","source":"Crossref","is-referenced-by-count":42,"title":["Efficacy, Tolerability and Patient Benefit of Ultrasound-Assisted Wound Treatment versus Surgical Debridement: A Randomized Clinical Study"],"prefix":"10.1159","volume":"222","author":[{"given":"Katharina","family":"Herberger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Franzke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Blome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Kirsten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Augustin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,4,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1524-475X.11.s2.1.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2001-19070"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2F0301-5629%2891%2990123-E"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2001-12651"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00000637-199408000-00004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.7638603"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02738539"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00403-009-0928-8"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1742-481X.2010.00732.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.c332"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/326116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/326116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:00:07Z","timestamp":1745434807000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000326116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2011,6,1]]},"published-print":{"date-parts":[[2011,6,29]]}},"URL":"https:\/\/doi.org\/10.1159\/000326116","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}