{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T16:28:04Z","timestamp":1777307284282,"version":"3.51.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2011]]},"abstract":"<i>Background:<\/i> Limited comparative data exist on the outcomes of patients presenting with chronic obstructive pulmonary disease (COPD) exacerbations with or without radiological pneumonia. <i>Objective:<\/i> To examine the outcome differences amongst these patients. <i>Methods:<\/i> We analysed 2008 UK National COPD audit data to examine the characteristics, management and outcomes, inpatient- and 90-day mortality and length of stay of patients admitted with COPD exacerbations. <i>Results:<\/i> Of 9,338 admissions, 16% (1,505) had changes consistent with pneumonia indicated on the admission chest X-ray. They tended to be older (mean ages 75 vs. 72 years), male (53 vs. 50%), more likely to come from care homes, with more disability, higher BMI and co-morbidity, lower albumin but higher urea levels, and less likely to be current smokers. COPD exacerbations with pneumonia were associated with worse outcomes: inpatient mortality was 11 and 7% and 90-day mortality was 17 and 13% for pneumonia and non-pneumonia patients, respectively (p < 0.001). After adjusting for factors that are significantly different between the 2 groups, including age, sex, place of residence, level of disability, co-morbidity, albumin and urea levels, estimated risk ratios for inpatient and 90-day mortality for pneumonia compared to non-pneumonia cases in this series were 1.19 (1.01,1.42) and 1.09 (0.96,1.23), respectively. The adjusted risk ratio of a prolonged acute hospital stay of more than 7 days was 1.15 (1.07, 1.23). <i>Conclusions: <\/i>Patients who present with radiological pneumonia have worse outcomes compared to those admitted without pneumonia in exacerbation of COPD.<\/jats:p>","DOI":"10.1159\/000327203","type":"journal-article","created":{"date-parts":[[2011,5,20]],"date-time":"2011-05-20T07:57:29Z","timestamp":1305878249000},"page":"320-327","source":"Crossref","is-referenced-by-count":54,"title":["UK National COPD Resources and Outcomes Project 2008: Patients with Chronic Obstructive Pulmonary Disease Exacerbations Who Present with Radiological Pneumonia Have Worse Outcome Compared to Those with Non-Pneumonic Chronic Obstructive Pulmonary Disease Exacerbations"],"prefix":"10.1159","volume":"82","author":[{"given":"Phyo Kyaw","family":"Myint","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Lowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhona J.","family":"Buckingham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Michael","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"British Thoracic Society and the Royal College of Physicians Clinical Effectiveness Evaluation Unit (CEEu)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,5,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136%2Fthorax.57.2.137"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136%2Fthorax.58.11.947"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136%2Fthx.2005.049940"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.97.10071530"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000213757"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.rmed.2007.05.011"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.06.00131905"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.117.3.662"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1164%2Frccm.200506-859OC"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.128.4.2005"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3109%2F00365549209054652"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.278.17.1440"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3109%2F02813439209014066"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2888%2991613-3"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/327203","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/327203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:11:35Z","timestamp":1745435495000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000327203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,9,1]]},"published-print":{"date-parts":[[2011,9,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000327203","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}