{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T14:06:50Z","timestamp":1792850810319,"version":"4.5.0"},"reference-count":59,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; While the prevalence of Alzheimer disease (AD) increases with age, little is known about the frequency of dementia with Lewy bodies (DLB) in the oldest old. A retrospective hospital-based study compared the relative prevalence of DLB among very old individuals. &lt;i&gt;Methods:&lt;\/i&gt; 1,100 consecutive autopsy cases of demented patients aged over 70 years (mean age: 83.9 \u00b1 5.4 years) were examined using standardized neuropathological methods and current diagnostic consensus criteria. &lt;i&gt;Results:&lt;\/i&gt; Evaluation of three age groups (8th\u201310th decade) showed a significant increase in the relative prevalence of AD with cerebrovascular lesions including mixed dementia, while AD with Lewy body (LB) pathology showed a mild but insignificant age-related increase. Both \u2018pure\u2019 AD and vascular dementia showed a mild but insignificant decline, while DLB (without severe AD pathology) decreased progressively. While the severity of Lewy pathology in DLB slightly decreased with age, concomitant Alzheimer-like pathology increased progressively. &lt;i&gt;Conclusion:&lt;\/i&gt; Whether DLB in the oldest old represents a distinct group is a matter of discussion, but the relative prevalence of AD with LB in our sample remained fairly stable.<\/jats:p>","DOI":"10.1159\/000327360","type":"journal-article","created":{"date-parts":[[2011,4,19]],"date-time":"2011-04-19T10:36:45Z","timestamp":1303209405000},"page":"309-316","source":"Crossref","is-referenced-by-count":47,"title":["Prevalence and Pathology of Dementia with Lewy Bodies in the Oldest Old: A Comparison with Other Dementing Disorders"],"prefix":"10.1159","volume":"31","author":[{"given":"Kurt 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