{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:34:09Z","timestamp":1792632849498,"version":"4.5.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Primary lymphoma of bone is extremely rare. There are increasing reports of lymphoma arising in bone adjacent to metallic prostheses. Herein, we describe the case of a 76-year-old man who developed diffuse large B cell lymphoma in the tibia 3 years after total knee arthroplasty for osteoarthritis. A review of the literature has identified 11 other cases of lymphoma arising in the context of orthopaedic metallic implants. To our knowledge this is the first reported case of a primary lymphoma arising in bone adjacent to a knee prosthesis. Possible pathogenetic mechanisms may include chronic antigenic stimulation of lymphocytes, proliferation of EBV-infected B lymphocytes, and direct mutagenic effects of metallic ions. Further research is required to investigate this intriguing link between metallic orthopaedic prostheses and localized lymphoma.<\/jats:p>","DOI":"10.1159\/000328202","type":"journal-article","created":{"date-parts":[[2011,7,6]],"date-time":"2011-07-06T10:42:06Z","timestamp":1309948926000},"page":"141-146","source":"Crossref","is-referenced-by-count":23,"title":["Diffuse Large B Cell Lymphoma Complicating Total Knee Arthroplasty: Case Report and Literature Review of the Association of Diffuse Large B Cell Lymphoma with Joint Replacement"],"prefix":"10.1159","volume":"126","author":[{"given":"Mohammed Suhail","family":"Chaudhry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harriet","family":"Mather","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Marks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kikkeri","family":"Naresh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,7,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1309%2FCMPGPYTMFRM6RVQR"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4065%2Fmcp.2010.0115"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F01.pas.0000157747.10967.f4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00402-008-0568-z"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2FRLU.0b013e318065a9cf"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1054%2Farth.2001.9827"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.arth.2005.11.002"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fjcp.51.8.629"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1080%2F1042819021000016140"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2559.1982.tb02776.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819810815%2948%3A4%3C1009%3A%3AAID-CNCR2820480426%3E3.0.CO%3B2-W"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00003086-199608001-00024"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.arth.2004.09.010"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3109%2F17453679908997851"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.10580"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.bjc.6602511"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1080%2F01676830802224817"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2FPAS.0b013e3181ce9128"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/328202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/328202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/328202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:19:12Z","timestamp":1745435952000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000328202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2011,9,1]]},"published-print":{"date-parts":[[2011,9,29]]}},"URL":"https:\/\/doi.org\/10.1159\/000328202","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}