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However, the theory of radiation-induced transformation does not rule out postirradiation sarcomas with a short latency period. We experienced the case of a patient with postirradiation leiomyosarcoma of the tongue, which occurred 19 months after he had received chemoradiotherapy. Besides the short latency period, a pseudotumor stage developed between the time of radiation exposure and the development of leiomyosarcoma. In this article, we also describe an immunohistochemical approach to diagnose leiomyosarcoma and the efficacy of a gemcitabine and docetaxel regimen.<\/jats:p>","DOI":"10.1159\/000328977","type":"journal-article","created":{"date-parts":[[2011,6,23]],"date-time":"2011-06-23T10:11:03Z","timestamp":1308823863000},"page":"201-205","source":"Crossref","is-referenced-by-count":7,"title":["Early-Onset Postirradiation Sarcoma of the Tongue after Pseudotumor Phase"],"prefix":"10.1159","volume":"73","author":[{"given":"Takushi","family":"Miyoshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Takebayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nao","family":"Hiwatashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Ono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Miura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,6,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%28194805%291%3A1%3C3%3A%3AAID-CNCR2820010103%3E3.0.CO%3B2-7"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%281971%2928%3A5%3C1087%3A%3AAID-CNCR2820280502%3E3.0.CO%3B2-F"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819940515%2973%3A10%3C2653%3A%3AAID-CNCR2820731030%3E3.0.CO%3B2-G"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.tripleo.2007.01.035"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.11164"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819910801%2968%3A3%3C524%3A%3AAID-CNCR2820680313%3E3.0.CO%3B2-E"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1017%2FS0022215100130117"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.304.6835.1137"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199603213341201"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1080%2F13577140310001650330"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02482828"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002%2Fijc.21867"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/328977","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/328977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:25:29Z","timestamp":1745436329000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000328977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,8,1]]},"published-print":{"date-parts":[[2011,8,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000328977","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.5241316","asserted-by":"subject"}]},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"type":"print","value":"0301-1569"},{"type":"electronic","value":"1423-0275"}],"subject":[],"published":{"date-parts":[[2011]]}}}