{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T08:13:45Z","timestamp":1778055225919,"version":"3.51.4"},"reference-count":10,"publisher":"S. Karger AG","issue":"Suppl. 1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res Paediatr"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Background\/Aims: Cardiovascular disease is the most prominent cause of mortality worldwide. A key risk factor for atherosclerotic cardiovascular disease is the presence of dyslipidemia. Clinical approaches to evaluation and treatment of dyslipidemia in children and adolescents are presented. Methods: A review of published guidelines and presentation of illustrative cases. Results: Dyslipidemia is an important risk factor in early-stage atherosclerosis. Children and adolescents at high risk for dyslipidemia can be identified using a positive family history or the presence of other risk factors as a trigger. Once high-risk individuals are identified, primary treatment is lifestyle modification. In cases where low-density lipoprotein-cholesterol is high, pharmacologic intervention may be needed. Conclusions: Screening of appropriate children and adolescents for dyslipidemia and treating those at high risk are important for the long-term prevention of cardiovascular disease.<\/jats:p>","DOI":"10.1159\/000329163","type":"journal-article","created":{"date-parts":[[2011,7,21]],"date-time":"2011-07-21T08:04:02Z","timestamp":1311235442000},"page":"47-51","source":"Crossref","is-referenced-by-count":10,"title":["Screening and Treatment of Dyslipidemias in Children and Adolescents"],"prefix":"10.1159","volume":"76","author":[{"given":"S.R.","family":"Daniels","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,7,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199806043382302"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.264.23.3018"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9149%2887%2990165-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161%2FCIRCULATIONAHA.106.179568"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161%2FCIRCULATIONAHA.107.181946"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.2008-1349"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.26.7.2194"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.295.13.1549"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.292.3.331"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2337%2Fdc06-9914"}],"container-title":["Hormone Research in Paediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/hrp\/article-pdf\/76\/Suppl.%201\/47\/4030198\/000329163.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/hrp\/article-pdf\/76\/Suppl.%201\/47\/4030198\/000329163.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:17:15Z","timestamp":1745432235000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000329163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":10,"journal-issue":{"issue":"Suppl. 1","published-online":{"date-parts":[[2011,7,1]]},"published-print":{"date-parts":[[2011,7,25]]}},"URL":"https:\/\/doi.org\/10.1159\/000329163","archive":["Portico"],"relation":{},"ISSN":["1663-2818","1663-2826"],"issn-type":[{"value":"1663-2818","type":"print"},{"value":"1663-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}