{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:15:13Z","timestamp":1760955313725,"version":"3.40.4"},"reference-count":22,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2011]]},"abstract":"<i>Background:<\/i> Hemorrhagic transformation (HT) is a well-known consequence of acute ischemic stroke, but little is known about HT in cerebellar infarction. <i>Methods:<\/i> Patients with acute cerebellar infarction within 48 h of onset were retrospectively recruited. MRI, including diffusion-weighted imaging (DWI) and T<sub>2<\/sub>*-gradient echo imaging (T<sub>2<\/sub>*), was performed twice (upon admission and 2 weeks after stroke onset). Infarct diameter and volume were measured by manual tracing on initial DWI. HT was evaluated with follow-up T<sub>2<\/sub>*, and all patients were divided into two groups according to the presence of HT (HT group and non-HT group). The frequency of HT and the factors associated with HT were investigated. <i>Results:<\/i> Ninety-six patients (64 males, median age 74 years, IQR 65\u201381 years, and National Institute of Health Stroke Scale score 5, IQR 1\u201314) were enrolled. Forty-two patients (43%) showed HT on follow-up T<sub>2<\/sub>* (HT group). Infarct diameter and volume were larger in the HT group than in the non-HT group (3.2 vs. 1.6 cm, respectively, p < 0.001, for infarct diameter and 8.0 vs. 1.7 cm<sup>3<\/sup>, respectively, p < 0.001 for infarct volume). Multivariate logistic regression analysis revealed that both infarct diameter >2.7 cm (OR 7.58, 95% CI 2.82\u201320.4, p < 0.001) and volume >4.5 cm<sup>3<\/sup> (OR 11.5, 95% CI 3.80\u201334.8, p < 0.001) were independent factors associated with HT. <i>Conclusions:<\/i> Half of the patients with acute cerebellar infarcts had HT on follow-up T<sub>2<\/sub>*. Initial infarct diameter and volume on DWI were independent factors associated with HT.<\/jats:p>","DOI":"10.1159\/000329259","type":"journal-article","created":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T10:55:54Z","timestamp":1316084154000},"page":"327-333","source":"Crossref","is-referenced-by-count":16,"title":["Hemorrhagic Transformation in Acute Cerebellar Infarction"],"prefix":"10.1159","volume":"32","author":[{"given":"Yuki","family":"Sakamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumi","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Iguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensaku","family":"Shibazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junya","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.17.2.179"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.24.3.465"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.20.5.598"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.30.11.2280"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.32.6.1330"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161%2FSTROKEAHA.107.510321"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jns.2008.05.012"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.28.5.957"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.30.7.1326"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.28.6.1198"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000316886"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs1201.99821"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.31.9.2062"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000227191.01792.e3"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.24.1.35"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.32.2.438"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1385%2FMN%3A28%3A3%3A229"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2FS0049-3848%2800%2900218-8"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.32.2.424"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1001%2Farchneur.58.4.621"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.292.15.1823"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1006%2Fexnr.1996.0137"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/329259","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/329259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:18:05Z","timestamp":1745432285000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000329259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,10,1]]},"published-print":{"date-parts":[[2011,10,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000329259","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"type":"print","value":"1015-9770"},{"type":"electronic","value":"1421-9786"}],"subject":[],"published":{"date-parts":[[2011]]}}}