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This disease typically occurs in association with systemic lupus erythematosus and a variety of other autoimmune diseases. We here describe an APF-like pustular eruption predominantly affecting the scalp, face and trunk, occurring during long-term infliximab treatment for Crohn\u2019s disease. Immunohistochemical staining of skin biopsy specimens for myxovirus resistance protein A, a marker for type 1 interferon-inducible proteins, showed increased staining in the epidermis and dermal mononuclear inflammatory infiltrate. Our observation further extends the spectrum of cutaneous adverse reactions potentially related to anti-tumor necrosis factor-\u03b1, the clinical context in which APF can occur as well as its clinical presentations.<\/jats:p>","DOI":"10.1159\/000329428","type":"journal-article","created":{"date-parts":[[2011,7,15]],"date-time":"2011-07-15T08:15:26Z","timestamp":1310717726000},"page":"304-310","source":"Crossref","is-referenced-by-count":28,"title":["Amicrobial Pustulosis-Like Rash in a Patient with Crohn\u2019s Disease under Anti-TNF-Alpha Blocker"],"prefix":"10.1159","volume":"222","author":[{"given":"Haur 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