{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:23:12Z","timestamp":1791116592630,"version":"4.1.0"},"reference-count":31,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2011,11,15]],"date-time":"2011-11-15T00:00:00Z","timestamp":1321315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,11,15]],"date-time":"2011-11-15T00:00:00Z","timestamp":1321315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Res"],"published-print":{"date-parts":[[2012]]},"abstract":"<i>Purpose:<\/i> To investigate the role of<i> Helicobacter pylori<\/i> in primary open-angle glaucoma (POAG) pathophysiology by detecting its presence in eye biopsies of POAG patients during trabeculectomy. <i>Patients and Methods:<\/i> Fifty-one consecutive patients who underwent trabeculectomy for POAG not responsive to antiglaucoma therapy, and 35 consecutive anemic controls were examined for <i>H. pylori<\/i> presence mainly by gastric mucosa histology. In POAG patients, eye biopsies were also obtained and stained for <i>H. pylori<\/i> presence in situ. <i>Results:<\/i> Forty-three of 51 (84.3%) POAG patients and 17 of 35 (48.6%) controls were tested <i>H. pylori<\/i> positive (p = 0.0004). In 5 <i>H. pylori<\/i>-positive POAG patients, <i>H. pylori<\/i> bacteria were identified in the trabeculum and iris specimens. <i>Conclusion:<\/i> For the first time, <i>H. pylori<\/i> bacteria have been detected histologically in eye biopsies of POAG patients.<\/jats:p>","DOI":"10.1159\/000330053","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T05:47:15Z","timestamp":1321422435000},"page":"150-156","source":"Crossref","is-referenced-by-count":46,"title":["Histological Presence of <i>Helicobacter pylori<\/i> Bacteria in the Trabeculum and Iris of Patients with Primary Open-Angle 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