{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:41:31Z","timestamp":1790077291740,"version":"4.0.1"},"reference-count":31,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2011]]},"abstract":"<i>Background:<\/i> Atrial fibrillation (AF) is a common cause of ischemic stroke and transient ischemic attack (TIA). More extensive diagnostic effort is required to detect paroxysmal AF (pxAF) than persistent AF (pAF); the prevalence of pxAF in stroke patients is unknown. We evaluated the prevalence of pAF and pxAF in ischemic stroke and TIA patients. <i>Methods:<\/i> Consecutive patients with acute ischemic stroke\/TIA were enrolled prospectively. We aimed to detect patients with a history of AF, with AF newly diagnosed in the emergency room (ER), or with newly diagnosed AF during a 3-month period following the event. Differences in the frequency of AF diagnosis with respect to the disposition of patients after ER work-up were assessed. <i>Results:<\/i> A total of 692 patients were enrolled (male: 52.2%; ischemic stroke: 69.1%; TIA: 30.9%). A previously documented history of AF was present in 19.7% (pAF: 47.1%, pxAF: 52.9%). In 3.8% of patients, AF was newly diagnosed in the ER (pxAF: 61.5%) and in 5.2% during the 3-month follow-up period. The overall prevalence of AF was 28.6% (pxAF: 62.6%). Previously documented pxAF evaded diagnosis at ER presentation in 48.6%. The prevalence of AF increased with age (p < 0.001). Patients with pxAF were younger than those with pAF (p = 0.004) and more often female (p = 0.05). The presence of any AF was associated with higher initial NIHSS scores (p < 0.001) and higher modified Rankin scores after 3 months (p < 0.001). <i>Conclusion: <\/i>pxAF occurs more often than pAF in stroke\/TIA patients. As effective stroke prevention is available for AF, it is important to develop and evaluate sensitive methods for detecting pxAF.<\/jats:p>","DOI":"10.1159\/000330348","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T21:39:10Z","timestamp":1492551550000},"page":"276-282","source":"Crossref","is-referenced-by-count":56,"title":["Paroxysmal Atrial Fibrillation Is More Prevalent than Persistent Atrial Fibrillation in Acute Stroke and Transient Ischemic Attack Patients"],"prefix":"10.1159","volume":"32","author":[{"given":"T.","family":"Rizos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Jenetzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.A.","family":"Ringleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Hacke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Veltkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,8,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jacc.2006.07.009"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.27.10.1765"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.22.8.983"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa0803778"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa0905561"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161%2FSTROKEAHA.107.181486"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000131083"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.154.13.1449"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000199147.30016.74"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161%2FCIR.0b013e31820f14c0"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jacc.2007.07.076"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093%2Feurheartj%2Fehn101"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093%2Feurheartj%2Fehn599"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1460-9592.2003.t01-1-00250.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1460-9592.2002.01587.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1540-8167.2006.00609.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159%2F000316885"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161%2FSTROKEAHA.106.478685"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1161%2FSTROKEAHA.110.591958"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1161%2FSTROKEAHA.107.492595"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093%2Feurheartj%2Fehq278"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000035735.49388.4A"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs1101.098637"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.305.6867.1460"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.28.12.2500"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs1001.097093"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000166053.83476.4a"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs1101.098524"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ahj.2010.03.032"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1053%2Fapmr.2000.6981"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.2004.048827"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/330348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/330348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:28:14Z","timestamp":1745432894000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000330348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":31,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2011,9,1]]},"published-print":{"date-parts":[[2011,9,29]]}},"URL":"https:\/\/doi.org\/10.1159\/000330348","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"value":"1015-9770","type":"print"},{"value":"1421-9786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}