{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T16:48:48Z","timestamp":1788022128354,"version":"build-2784847793"},"reference-count":16,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Vaginal metastasis from organs other than the uterus is rare. Generally, patients with vaginal metastasis from colorectal cancer have a dismal prognosis. Although biopsy is the best method to make the diagnosis, massive bleeding may occur. On the other hand, liquid-based cytology (LBC) has the utility to perform immunocytochemistry on additional unstained slides: we can make a diagnosis with several immunocytochemical findings. &lt;i&gt;Case:&lt;\/i&gt; A 67-year-old postmenopausal female presented to our hospital with vaginal bleeding. The patient had undergone colectomy because of her stage III sigmoid colon cancer 3 years earlier. The patient had also undergone hysterectomy for cervical cancer 30 years earlier. LBC from the vaginal stump revealed adenocarcinoma. Immunocytochemically, cancer cells were negative for cytokeratin 7 and positive for cytokeratin 20, which suggested metastasis from the sigmoid colon cancer; the diagnosis was made without a biopsy. &lt;i&gt;Conclusion:&lt;\/i&gt; When the patient has a metastatic lesion from colon adenocarcinoma, LBC with immunocytochemistry is useful in making a diagnosis.<\/jats:p>","DOI":"10.1159\/000330815","type":"journal-article","created":{"date-parts":[[2012,1,6]],"date-time":"2012-01-06T18:37:40Z","timestamp":1325875060000},"page":"92-96","source":"Crossref","is-referenced-by-count":11,"title":["Vaginal Stump Metastasis from Sigmoid Colon Cancer"],"prefix":"10.1159","volume":"56","author":[{"given":"Tomohito","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayoshi","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Sakaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Munakata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahide","family":"Ohmichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,1,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093%2Fjjco%2Fhyp150"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2407-6-31"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00404-009-1115-z"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3322%2Fcaac.20006"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1471-0528.1951.tb04037.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3109%2F00016346609158447"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3109%2F00016346609158466"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1006%2Fgyno.1993.1111"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F00008469-200102000-00009"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097%2F00008469-200102000-00009"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2559.2002.01387.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0959-8049%2802%2900008-4"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038%2Fmodpathol.3880175"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.20202"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2303.2008.00560.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00428-010-1025-2"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/330815","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/330815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:33:14Z","timestamp":1745433194000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000330815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,2,1]]},"published-print":{"date-parts":[[2012,1,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000330815","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"value":"0001-5547","type":"print"},{"value":"1938-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}