{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:35:10Z","timestamp":1745469310538,"version":"3.40.4"},"reference-count":5,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2011,10,20]],"date-time":"2011-10-20T00:00:00Z","timestamp":1319068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,10,20]],"date-time":"2011-10-20T00:00:00Z","timestamp":1319068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To report a case of severe abdominal bruising successfully diagnosed using systematic hemostatic investigations. &lt;i&gt;Clinical Presentation and Intervention:&lt;\/i&gt; A 60-year-old woman developed a large spontaneous nontraumatic, painless bruise over the right lower abdominal wall. Computed tomographic scan of the abdomen showed a subcutaneous hematoma beneath the site of the obvious bruise diagnosed as a hematoma. Laboratory tests revealed an activated partial thromboplastin time of 53 s and a factor VIII level of &lt;1%, consistent with the diagnosis of acquired hemophilia A. The patient was treated with steroids and immunosuppressants and her factor VIII levels gradually normalized. &lt;i&gt;Conclusion:&lt;\/i&gt; This case report showed that whenever there is spontaneous bruising, factor VIII deficiency should be considered as one of the important differential diagnosis.<\/jats:p>","DOI":"10.1159\/000331808","type":"journal-article","created":{"date-parts":[[2011,12,2]],"date-time":"2011-12-02T16:46:00Z","timestamp":1322844360000},"page":"86-88","source":"Crossref","is-referenced-by-count":0,"title":["A Large Spontaneous Abdominal Bruise in a 60-Year-Old Woman: A Case Report"],"prefix":"10.1159","volume":"21","author":[{"given":"Sujatha","family":"Mogili","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Woodlock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,10,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1182%2Fasheducation-2006.1.432"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182%2Fblood-2008-03-143586"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1468-0734.2001.00049.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2141.2003.04162.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00043426-200307000-00018"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/331808","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/331808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:43:47Z","timestamp":1745433827000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000331808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,20]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2011,12,1]]},"published-print":{"date-parts":[[2011,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000331808","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"type":"print","value":"1011-7571"},{"type":"electronic","value":"1423-0151"}],"subject":[],"published":{"date-parts":[[2011,10,20]]}}}