{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:16:16Z","timestamp":1762917376452,"version":"3.40.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2011,12,22]],"date-time":"2011-12-22T00:00:00Z","timestamp":1324512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,12,22]],"date-time":"2011-12-22T00:00:00Z","timestamp":1324512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To determine whether potassium chloride (KCl)-induced feticide prior to termination by dilation and evacuation (D&amp;#38;E) improves surgical outcome. &lt;i&gt;Methods:&lt;\/i&gt; We conducted a retrospective study of women who underwent second-trimester (13 0\/7 to 23 6\/7 weeks) D&amp;#38;E at an urban university-based hospital between January 2000 and July 2010. Women were divided into 3 cohorts: (1) D&amp;#38;E for termination of pregnancy after feticide, (2) D&amp;#38;E without feticide, and (3) D&amp;#38;E for spontaneous pregnancy loss. We compared maternal characteristics, various perioperative variables, and surgical outcomes for all 3 groups. Anesthesia time was used as a surrogate for operative time in the primary outcome. &lt;i&gt;Results:&lt;\/i&gt; We analyzed 128 pregnancies (group 1: n = 23, group 2: n = 53, group 3: n = 52). Baseline maternal characteristics did not differ among the 3 groups. Anesthesia time was longest in the termination with KCl group (group 1: 116.9 min vs. group 2: 94.5 min and group 3: 90.3 min, p = 0.004), however, the effect was mitigated after controlling for fetal size (p = 0.176). There was no difference in blood loss (p = 0.968). Complications were uncommon, however, cervical lacerations were more common in the termination with KCl group (2 vs. 0 and 0, p = 0.010). &lt;i&gt;Conclusion:&lt;\/i&gt; Presurgical feticide with KCl was not associated with shorter anesthesia time. The decision to perform feticide should be based on other considerations, such as patient preference.<\/jats:p>","DOI":"10.1159\/000333815","type":"journal-article","created":{"date-parts":[[2011,12,22]],"date-time":"2011-12-22T09:01:40Z","timestamp":1324544500000},"page":"63-68","source":"Crossref","is-referenced-by-count":9,"title":["Fetal Intracardiac Potassium Chloride Injection to Expedite Second-Trimester Dilation and Evacuation"],"prefix":"10.1159","volume":"31","author":[{"given":"Sareena","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil S.","family":"Seligman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Berghella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2011,12,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.contraception.2010.01.018"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000068068"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1471-0528.2007.01639.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000076714"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1469-0705.2002.00797.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1067%2Fmob.2002.127456"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0029-7844%2800%2901148-0"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093%2Fhumupd%2Fdml049"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/333815","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/333815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:42:05Z","timestamp":1745433725000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000333815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,22]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,2,1]]},"published-print":{"date-parts":[[2012,2,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000333815","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"type":"print","value":"1015-3837"},{"type":"electronic","value":"1421-9964"}],"subject":[],"published":{"date-parts":[[2011,12,22]]}}}