{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:13:50Z","timestamp":1785352430318,"version":"3.55.0"},"reference-count":29,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;i&gt;Aim:&lt;\/i&gt; To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias. &lt;i&gt;Methods:&lt;\/i&gt; A secondary analysis of a randomized controlled study in 70 patients with Parkinson\u2019s disease dementia (PDD) or dementia with Lewy bodies (DLB) over 24 weeks using caregiver-rated QOL-Alzheimer\u2019s disease (AD) in domains according to the WHO\u2019s classification of health. &lt;i&gt;Results:&lt;\/i&gt; Baseline QOL shows lower ratings for body functions over environmental factors in DLB\/PDD. Treatment with memantine significantly improves life as a whole compared to placebo and improves total QOL, body function and structure. &lt;i&gt;Conclusion:&lt;\/i&gt; This study shows that memantine improves QOL in Lewy body dementias. We also demonstrate important QOL patterns which can be used in clinical practice.<\/jats:p>","DOI":"10.1159\/000334523","type":"journal-article","created":{"date-parts":[[2011,11,25]],"date-time":"2011-11-25T09:17:08Z","timestamp":1322212628000},"page":"227-234","source":"Crossref","is-referenced-by-count":40,"title":["Quality of Life and the Effect of Memantine in Dementia with Lewy Bodies and Parkinson\u2019s Disease Dementia"],"prefix":"10.1159","volume":"32","author":[{"given":"Victoria","family":"Larsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Engedal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dag","family":"Aarsland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Wattmo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Minthon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabet","family":"Londos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2011,11,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1212%2F01.wnl.0000256715.13907.d3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1212%2F01.wnl.0000187889.17253.b1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159%2F000165917"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2FWAD.0b013e318065c4a9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fgps.1075"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000026556"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00002093-200204000-00008"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa041470"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159%2F000305100"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002%2F14651858.CD003154.pub5"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1750-3639.2004.tb00082.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS1474-4422%2809%2970146-2"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2800%2903399-7"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.2005.072983"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2FWAD.0b013e318047df4c"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080%2F03610730902720521"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002%2Fgps.550"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159%2F000149584"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1177%2F1533317506290589"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002%2Fgps.1619"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1037%2F0882-7974.5.1.127"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1176%2Fappi.ajgp.12.3.272"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1532-5415.2001.49210.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2702.2008.02537.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007%2Fs11136-006-0025-9"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1017%2FS0033291706009469"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007%2FBF00894357"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1159%2F000109923"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2318-7-16"}],"container-title":["Dementia and Geriatric Cognitive Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/334523","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/334523","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:48:47Z","timestamp":1745434127000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000334523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":29,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2012,2,1]]},"published-print":{"date-parts":[[2012,2,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000334523","archive":["Portico"],"relation":{},"ISSN":["1420-8008","1421-9824"],"issn-type":[{"value":"1420-8008","type":"print"},{"value":"1421-9824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}