{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:35:28Z","timestamp":1767828928272,"version":"3.49.0"},"reference-count":20,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Nephrol"],"published-print":{"date-parts":[[2012]]},"abstract":"<i>Background:<\/i> The relationship of routine postoperative troponin I (TnI) monitoring in kidney transplant recipients and in-hospital myocardial infarction (MI) is not known. <i>Methods:<\/i> This observational study evaluated the prevalence of abnormal postoperative TnI (Ortho Clinical Diagnostics assay) in 376 consecutive kidney or kidney\/pancreas transplant recipients. In-hospital MI was adjudicated using the universal definition. Rates of death and coronary revascularizations at 1 year were studied. Logistic regression analysis was performed to identify independent predictors of abnormal TnI. <i>Results:<\/i> Ninety-five (25%) recipients had abnormal TnI (>0.04 ng\/ml) following transplantation. Abnormal TnI levels were more common in older (mean age: 52.2 \u00b1 13.4 vs. 48.3 \u00b1 13.2 years, p = 0.01), diabetic (57.9 vs. 45.6%, p = 0.04), and prior coronary artery disease (31.6 vs. 20.3%, p = 0.02) patients. In-hospital MI occurred in 6 patients (1.6%). All subsequent in-hospital cardiovascular events occurred in the abnormal postoperative TnI group; most in those with TnI levels >1 ng\/ml. Previous coronary artery disease was the only independent predictor of a postoperative TnI level >1 ng\/ml in multivariate analysis (odds ratio 4.61, 95% confidence interval 1.49\u201314.32). At 1 year there was no significant difference in death (3.2 vs. 1.8%, p = 0.42) and borderline significant difference in coronary revascularization (5.3 vs. 1.4%, p = 0.049) in abnormal versus normal TnI groups. <i>Conclusions:<\/i> In-hospital MI was infrequent, but abnormal TnI highly prevalent following renal transplantation. Normal TnI levels following renal transplantation had a high negative predictive value in excluding patients likely to develop subsequent postoperative MI. The role of a higher TnI cut-off for screening for postoperative MI in high-risk subgroups deserves future prospective evaluation.<\/jats:p>","DOI":"10.1159\/000335679","type":"journal-article","created":{"date-parts":[[2012,1,25]],"date-time":"2012-01-25T09:54:04Z","timestamp":1327485244000},"page":"175-180","source":"Crossref","is-referenced-by-count":13,"title":["Troponin I Levels and Postoperative Myocardial Infarction following Renal Transplantation"],"prefix":"10.1159","volume":"35","author":[{"given":"G.R.","family":"Shroff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.K.","family":"Akkina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.D.","family":"Miedema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Madlon-Kay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.A.","family":"Herzog","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.L.","family":"Kasiske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,1,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199809173391203"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-6143.2009.02949.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199912023412303"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1503%2Fcmaj.050011"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F01.tp.0000235527.81917.fe"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1373%2Fclinchem.2005.055665"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2005.11.026"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161%2F01.CIR.0000041254.30637.34"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2Fgfm738"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-6143.2008.02395.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-6143.2009.02636.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2FTP.0b013e3181bc405e"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2362.2007.01785.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1440-1797.2006.00661.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136%2Fhrt.2008.151233"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136%2Fhrt.2005.069666"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1161%2FCIR.0b013e3181d839e8"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1399-0012.2001.150302.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1681%2FASN.2004070580"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1213%2F01%2Fane.0000309024.28586.70"}],"container-title":["American Journal of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/335679","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/335679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:59:41Z","timestamp":1745434781000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000335679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2012,2,1]]},"published-print":{"date-parts":[[2012,2,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000335679","archive":["Portico"],"relation":{},"ISSN":["0250-8095","1421-9670"],"issn-type":[{"value":"0250-8095","type":"print"},{"value":"1421-9670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}